Rebif and Levemir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rebif (interferon beta-1a) and Levemir (insulin detemir recombinant). Common drug interactions include fall among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Rebif and Levemir. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Rebif?

Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.

What is Levemir?

Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.

On Jul, 15, 2026

15 people who take Rebif and Levemir together, and have interactions are studied.

What are the common drug interactions of Rebif and Levemir, by gender? *:

female:

Fall
Headache (pain in head)
Injection site mass
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dyspnoea (difficult or laboured respiration)
Pain
Renal failure acute (rapid kidney dysfunction)
Asthenia (weakness)
Breast disorder
Carotid artery disease

male:

Fall
Renal impairment (severely reduced kidney function)
Diarrhoea
Faecal incontinence (a lack of control over passing stool)
Fungal infection
General physical health deterioration (weak health status)
Glycosylated haemoglobin increased
Hepatomegaly (abnormal enlargement of the liver)
Inflammation
Muscular weakness (muscle weakness)

What are the common drug interactions of Rebif and Levemir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Lower respiratory tract infection
Malaise (a feeling of general discomfort or uneasiness)

30-39:

Anxiety
Chest pain
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fatigue (feeling of tiredness)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hypergammaglobulinaemia benign monoclonal (elevated levels of gamma globulin)
Pain
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Asthenia (weakness)
Headache (pain in head)
Abasia (inability to walk)
Arthralgia (joint pain)
Back pain
Blood creatinine increased
Blood glucose increased
Blood iron decreased
Bone disorder
Breast cellulitis (spreading, acute inflammation of beast skin)

50-59:

Fall
Anal injury
Cardiac valve disease (heart valve disease)
Cardiomegaly (increased size of heart than normal)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fungal infection
Glycosylated haemoglobin increased
Hepatomegaly (abnormal enlargement of the liver)
Inflammation
Muscular weakness (muscle weakness)

60+:

Breast disorder
Carotid artery disease
Insomnia (sleeplessness)
Muscular weakness (muscle weakness)
Night blindness (inability to see in night as day)
Renal impairment (severely reduced kidney function)
Thyroid disorder (thyroid diseases)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Weight decreased
Interstitial lung disease

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 33.33%
Type 2 Diabetes: 2 people, 13.33%
Pain: 2 people, 13.33%
High Blood Cholesterol: 2 people, 13.33%
Depression: 2 people, 13.33%
Type 1 Diabetes: 1 person, 6.67%
Sleep Disorder: 1 person, 6.67%
Serum Ferritin Increased: 1 person, 6.67%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 6.67%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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