Reglan and Enulose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Enulose (lactulose). Common drug interactions include asthenia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Reglan and Enulose. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

35 people who take Reglan and Enulose together, and have interactions are studied.

What are the common drug interactions of Reglan and Enulose, by gender? *:

female:

Asthenia (weakness)
Pain
Balance disorder
Dizziness
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Vomiting
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Arthralgia (joint pain)
Confusional state
Fall
Gait disturbance
Generalised oedema (swelling all over the body)
Hypotension (abnormally low blood pressure)
Acquired oesophageal web (structural abnormalities in the oesophagus)
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase decreased
Anxiety

What are the common drug interactions of Reglan and Enulose, by age (0-1 to 60+)? *:

0-1:

Cystic fibrosis (disease of the secretary glands)
Hypoxia (low oxygen in tissues)
Pulmonary artery stenosis (narrowing (stenosis) that occurs in the lung artery)
Tricuspid valve disease (disease of heart valve)
Venous thrombosis (blood clot (thrombus) that forms within a vein)
Vocal cord paralysis
Vomiting
Weight gain poor

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal injury (kidney injury)

40-49:

Confusional state
Device related infection
Fall
Implant site infection
Infusion related reaction
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

Jaundice cholestatic
Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen)
Metastases to liver (cancer spreads to liver)
Metastases to peritoneum (cancer spreads to peritoneum)
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Alanine aminotransferase increased
Blood bilirubin increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

60+:

Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Blood albumin decreased
Haemoglobin decreased
Metastases to bone (cancer spreads to bone)
Balance disorder
Vomiting
Gait disturbance
Generalised oedema (swelling all over the body)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Pain: 15 people, 42.86%
Stress And Anxiety: 11 people, 31.43%
Nausea (feeling of having an urge to vomit): 11 people, 31.43%
Depression: 9 people, 25.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 20.00%
Pancreatic Carcinoma (pancreatic cancer): 7 people, 20.00%
Breast Cancer: 6 people, 17.14%
Metastases To Bone (cancer spreads to bone): 6 people, 17.14%
Prostate Cancer: 6 people, 17.14%
Hypersensitivity: 6 people, 17.14%

* Approximation only. Some reports may have incomplete information.

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