Reglan and Patanase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Patanase (olopatadine hydrochloride). Common drug interactions include death among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Reglan and Patanase. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
What is Patanase?
Patanase has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,514 Patanase users. Check the latest studies of Patanase.
20 people who take Reglan and Patanase together, and have interactions are studied.

What are the common drug interactions of Reglan and Patanase, by gender? *:
female:
- Death
- Heart rate increased
- Hypertension (high blood pressure)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Abdominal discomfort
- Hysterectomy
- Pulmonary oedema (fluid accumulation in the lungs)
- Therapeutic response unexpected
- Abdominal distension
- Acute respiratory failure
male:
- Dyspnoea (difficult or laboured respiration)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Osteonecrosis (death of bone)
- Oxygen saturation decreased
- Pain
- Pneumonia
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Rhinovirus infection
- Tooth loss
What are the common drug interactions of Reglan and Patanase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Cardiac disorder
- Dyspnoea (difficult or laboured respiration)
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
- Oxygen saturation decreased
- Pneumonia
- Pyrexia (fever)
- Rhinovirus infection
- Urinary tract infection
- Osteoporosis (bones weak and more likely to break)
20-29:
- Heart rate increased
- Hypertension (high blood pressure)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
30-39:
- Death
- Heart rate increased
- Hypertension (high blood pressure)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Pulmonary oedema (fluid accumulation in the lungs)
40-49:
n/a
50-59:
- Abdominal discomfort
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone loss
- Chronic kidney disease
- Emotional distress
- Hysterectomy
- Multiple fractures
- Osteonecrosis (death of bone)
- Pain
60+:
- Abdominal distension
- Acute respiratory failure
- Hearing impaired
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypokalaemia (low potassium)
- Hypotension (abnormally low blood pressure)
- Incisional hernia (hernia caused by an incompletely-healed surgical wound)
- Lactic acidosis (low ph in body tissues)
- Lethargy (tiredness)
- Lip dry
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 20.00%
- Lung Disorder (lung disease): 3 people, 15.00%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 10.00%
- Scoliosis (a medical condition in which a person's spine is curved from side to side): 2 people, 10.00%
- Cystic Fibrosis (disease of the secretary glands): 2 people, 10.00%
- Lipidosis (disorder of lipid metabolism involving abnormal accumulation of lipids in the reticuloendothelial cells): 2 people, 10.00%
- Hiv Infection: 2 people, 10.00%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 10.00%
- Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 1 person, 5.00%
- Hypersensitivity: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Reglan and Patanase?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Reglan and Patanase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Patanase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Patanase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and olopatadine hydrochloride (the active ingredients of Reglan and Patanase, respectively), and Reglan and Patanase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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