Reglan and Pegasys drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Pegasys (peginterferon alfa 2a). Common drug interactions include dizziness among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Reglan and Pegasys. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Pegasys?

Pegasys has active ingredients of peginterferon alfa 2a. It is often used in hepatitis c. eHealthMe is studying from 57,446 Pegasys users. Check the latest studies of Pegasys.



On Aug, 07, 2026

34 people who take Reglan and Pegasys together, and have interactions are studied.

Reglan and Pegasys drug interactions.

What are the common drug interactions of Reglan and Pegasys, by gender? *:

female:

  1. Dizziness
  2. Blood thyroid stimulating hormone increased
  3. Cerebral thrombosis (blood clot in brain)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Headache (pain in head)
  8. Lethargy (tiredness)
  9. Migraine (headache)
  10. Neuropathy peripheral (surface nerve damage)

male:

  1. Fatigue (feeling of tiredness)
  2. Depression
  3. Headache (pain in head)
  4. Insomnia (sleeplessness)
  5. Memory impairment
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Neck pain
  8. White blood cell count decreased
  9. Abnormal behaviour
  10. Anti-erythropoietin antibody positive

What are the common drug interactions of Reglan and Pegasys, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cerebral thrombosis (blood clot in brain)
  2. Headache (pain in head)
  3. Migraine (headache)
  4. Vision blurred
  5. Abdominal pain
  6. Blood calcium decreased
  7. Crying
  8. Dehydration (dryness resulting from the removal of water)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Dizziness

40-49:

  1. Anaemia (lack of blood)
  2. Blood thyroid stimulating hormone increased
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Lethargy (tiredness)
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Stomatitis (inflammation of mucous membrane of mouth)
  8. Abdominal distension
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

50-59:

  1. Leukopenia (less number of white blood cells in blood)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Pneumonia
  4. Thrombocytopenia (decrease of platelets in blood)
  5. Anti-erythropoietin antibody positive
  6. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  7. Back pain
  8. Injection site swelling
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. White blood cell count decreased

60+:

  1. Pruritus (severe itching of the skin)
  2. Bipolar disorder (mood disorder)
  3. Gait disturbance
  4. Haematocrit decreased
  5. Homicidal ideation (thoughts about human killing another human)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Rash generalised (rash on most of body parts)

What are the existing conditions these people have? *

  1. Sleep Disorder: 7 people, 20.59%
  2. Pain: 5 people, 14.71%
  3. High Blood Pressure: 5 people, 14.71%
  4. Neck Pain: 4 people, 11.76%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
  6. Depression: 3 people, 8.82%
  7. White Blood Cell Count Decreased: 2 people, 5.88%
  8. Stress And Anxiety: 2 people, 5.88%
  9. Nausea (feeling of having an urge to vomit): 2 people, 5.88%
  10. Indigestion: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Reglan and Pegasys?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Reglan and Pegasys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pegasys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reglan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pegasys and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride and peginterferon alfa 2a (the active ingredients of Reglan and Pegasys, respectively), and Reglan and Pegasys (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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