Reglan and Unasyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Unasyn (ampicillin sodium; sulbactam sodium). Common drug interactions include pleural effusion among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Reglan and Unasyn. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Unasyn?

Unasyn has active ingredients of ampicillin sodium; sulbactam sodium. eHealthMe is studying from 4,474 Unasyn users. Check the latest studies of Unasyn.

On Jul, 04, 2026

74 people who take Reglan and Unasyn together, and have interactions are studied.

What are the common drug interactions of Reglan and Unasyn, by gender? *:

female:

Pleural effusion (water on the lungs)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Deformity (disfigurement)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Emotional distress
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Intervertebral disc degeneration (spinal disc degeneration)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Tooth loss

male:

Anaemia (lack of blood)
Anxiety
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)
Rib fracture
Spinal cord compression
Thrombocytopenia (decrease of platelets in blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)

What are the common drug interactions of Reglan and Unasyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Methaemoglobinaemia (a disorder characterized by the presence of a higher than normal level of methemoglobin in blood)
Platelet count decreased
Renal failure (kidney dysfunction)

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

Anxiety
Diarrhoea
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Deformity (disfigurement)
Emotional distress
Intervertebral disc degeneration (spinal disc degeneration)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Dizziness
Dyspnoea (difficult or laboured respiration)

50-59:

Blood pressure increased
Cardiac failure
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Chest pain
Chills (felling of cold)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Culture wound positive

60+:

Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Osteoporosis (bones weak and more likely to break)
Pain
Rib fracture
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bone disorder

What are the existing conditions these people have? *

Osteopenia (a condition where bone mineral density is lower than normal): 17 people, 22.97%
Multiple Myeloma (cancer of the plasma cells): 9 people, 12.16%
Pain: 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

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