Reglan and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Vimpat (lacosamide). Common drug interactions include sinusitis among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Reglan and Vimpat. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

On Jul, 09, 2026

43 people who take Reglan and Vimpat together, and have interactions are studied.

What are the common drug interactions of Reglan and Vimpat, by gender? *:

female:

Sinusitis (inflammation of sinus)
Skin exfoliation (removal of the oldest dead skin cells)
Staring (a prolonged gaze or fixed look)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thalamus haemorrhage (bleeding in thalamus)
Therapeutic response unexpected
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Unresponsive to stimuli
Vulvovaginal discomfort

male:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cough
Abdominal discomfort
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Decreased appetite
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Hypertension (high blood pressure)

What are the common drug interactions of Reglan and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Swelling
Abdominal discomfort
Cough
Flatulence (flatus expelled through the anus)
Regurgitation (expulsion of material)
Sedation
Vomiting
Impaired gastric emptying
Rhinovirus infection
Somnolence (a state of near-sleep, a strong desire for sleep)

10-19:

n/a

20-29:

Chronic kidney disease
Device failure
Drug ineffective
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

30-39:

Abdominal pain upper

40-49:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Fall
Fungal skin infection
Hypokalaemia (low potassium)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Urinary tract infection bacterial
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Urinary tract infection
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Addison's disease (addison's disease, a hormonal disorder disease)
Hypersomnia (excessive daytime sleepiness (eds))
Lethargy (tiredness)
Diarrhoea
Fall
Fungal skin infection
Hypokalaemia (low potassium)

60+:

Pyrexia (fever)
Urinary tract infection
Hepatitis a
Hypertension (high blood pressure)
Malignant neoplasm progression (cancer tumour came back)
Pain
Vomiting
Weight decreased
Dysphagia (a condition in which swallowing is difficult or painful)
Feeling hot

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 11 people, 25.58%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 18.60%
Migraine (headache): 7 people, 16.28%
High Blood Pressure: 6 people, 13.95%
Partial Seizures (seizures which affect only a part of the brain at onset): 5 people, 11.63%
Pain: 5 people, 11.63%
Constipation: 5 people, 11.63%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 5 people, 11.63%
Stress And Anxiety: 5 people, 11.63%
Gout (uric acid crystals building up in the body): 5 people, 11.63%

* Approximation only. Some reports may have incomplete information.

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