Relafen and Altace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Relafen (nabumetone) and Altace (ramipril). Common drug interactions include arthralgia among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Relafen and Altace. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.
What is Relafen?
Relafen has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 6,243 Relafen users. Check the latest studies of Relafen.
What is Altace?
Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,681 Altace users. Check the latest studies of Altace.
65 people who take Relafen and Altace together, and have interactions are studied.

What are the common drug interactions of Relafen and Altace, by gender? *:
female:
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dyspnoea (difficult or laboured respiration)
- International normalised ratio increased
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Tension (the act or process of stretching something tight)
- Vitamin d deficiency
- Blood urea increased
male:
- Back pain
- Headache (pain in head)
- Fatigue (feeling of tiredness)
- Iron deficiency anaemia
- Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
- Memory impairment
- Anxiety
- Arthralgia (joint pain)
- Cough
- Erectile dysfunction
What are the common drug interactions of Relafen and Altace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Back pain
- Headache (pain in head)
- Drug abuser
- Haematemesis (vomiting of blood)
- Asthenia (weakness)
- Iron deficiency anaemia
- Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Erectile dysfunction
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
50-59:
- Arteriosclerosis (thickening and hardening of arteries)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Blood creatinine increased
- Blood urea increased
- Bone disorder
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
60+:
- Asthenia (weakness)
- Cough
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- International normalised ratio increased
- Memory impairment
- Oedema peripheral (superficial swelling)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Tension (the act or process of stretching something tight)
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 12.31%
- Pain: 8 people, 12.31%
- Metastases To Bone (cancer spreads to bone): 7 people, 10.77%
- Breast Cancer: 7 people, 10.77%
- Diabetes: 5 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Relafen and Altace?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Relafen and Altace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Relafen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Altace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Relafen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Altace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
- Hung SC, Liao KF, Hung HC, Lin CL, Lai SW, Lin CH, "Nabumetone use and risk of acute pancreatitis in a case-control study", Pancreatology, 2016 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on nabumetone and ramipril (the active ingredients of Relafen and Altace, respectively), and Relafen and Altace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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