Relistor and Losartan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Relistor (methylnaltrexone bromide) and Losartan (losartan potassium). Common drug interactions include agitation among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Relistor and Losartan. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Relistor?

Relistor has active ingredients of methylnaltrexone bromide. eHealthMe is studying from 1,659 Relistor users. Check the latest studies of Relistor.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 177,686 Losartan users. Check the latest studies of Losartan.



On Jul, 22, 2026

22 people who take Relistor and Losartan together, and have interactions are studied.

Relistor and Losartan drug interactions.

What are the common drug interactions of Relistor and Losartan, by gender? *:

female:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety
  3. Arthropathy
  4. Asthenia (weakness)
  5. Back pain
  6. Body height decreased
  7. Cardiac disorder
  8. Constipation
  9. Dry mouth
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

male:

  1. Drug ineffective
  2. Weight increased
  3. Circulatory collapse
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Interstitial lung disease
  6. Pruritus generalised (generalized itching)
  7. Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Relistor and Losartan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Hepatic enzyme increased
  3. Liver disorder (liver diseases)

50-59:

  1. Drug ineffective
  2. Accident at home
  3. Agitation (state of anxiety or nervous excitement)
  4. Anxiety
  5. Arthropathy
  6. Asthenia (weakness)
  7. Back pain
  8. Body height decreased
  9. Cardiac disorder
  10. Constipation

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Asthenia (weakness)
  4. Back pain
  5. Body height decreased
  6. Cardiac disorder
  7. Constipation
  8. Defaecation urgency (a sudden compelling urge to defecate)
  9. Dry mouth
  10. Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

  1. Constipation: 11 people, 50.00%
  2. Pain: 9 people, 40.91%
  3. High Blood Cholesterol: 8 people, 36.36%
  4. Diabetes: 8 people, 36.36%
  5. Neuralgia (pain in one or more nerves): 7 people, 31.82%
  6. Glossitis (infection of tongue with soreness): 6 people, 27.27%
  7. Lung Disorder (lung disease): 6 people, 27.27%
  8. Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 27.27%
  9. Thyroid Diseases: 6 people, 27.27%
  10. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Relistor and Losartan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Relistor and Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Relistor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Losartan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Relistor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Losartan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methylnaltrexone bromide and losartan potassium (the active ingredients of Relistor and Losartan, respectively), and Relistor and Losartan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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