Relpax and Brintellix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Relpax (eletriptan hydrobromide) and Brintellix (vortioxetine hydrobromide). Common drug interactions include cardiac disorder among females and eye pain among males.

The phase IV clinical study analyzes what interactions people have when they take Relpax and Brintellix. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Relpax?

Relpax has active ingredients of eletriptan hydrobromide. It is often used in migraine. eHealthMe is studying from 9,259 Relpax users. Check the latest studies of Relpax.

What is Brintellix?

Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,748 Brintellix users. Check the latest studies of Brintellix.



On Jul, 09, 2026

15 people who take Relpax and Brintellix together, and have interactions are studied.

Relpax and Brintellix drug interactions.

What are the common drug interactions of Relpax and Brintellix, by gender? *:

female:

  1. Cardiac disorder
  2. Drug hypersensitivity
  3. Drug ineffective
  4. Fall
  5. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
  6. Haematochezia (passage of stools containing blood)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  9. Hypotension (abnormally low blood pressure)
  10. Intracardiac mass (cardiac mass)

male:

  1. Eye pain
  2. Headache (pain in head)

What are the common drug interactions of Relpax and Brintellix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Eye pain
  2. Headache (pain in head)

50-59:

  1. Bowel movement irregularity
  2. Drug hypersensitivity
  3. Drug ineffective
  4. Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
  5. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Nephrolithiasis (calculi in the kidneys)
  8. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  9. Rash
  10. Sinusitis (inflammation of sinus)

60+:

  1. Cardiac disorder
  2. Haematochezia (passage of stools containing blood)
  3. Hypotension (abnormally low blood pressure)
  4. Intracardiac mass (cardiac mass)
  5. Myalgia (muscle pain)
  6. Neoplasm (tumour)
  7. Vision blurred

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
  2. Stress And Anxiety: 2 people, 13.33%
  3. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 13.33%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%
  7. Pain: 1 person, 6.67%
  8. Neuralgia (pain in one or more nerves): 1 person, 6.67%
  9. Nausea (feeling of having an urge to vomit): 1 person, 6.67%
  10. Sinus Congestion (blockage of sinus): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Relpax and Brintellix?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Relpax and Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Relpax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Brintellix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Relpax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Brintellix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on eletriptan hydrobromide and vortioxetine hydrobromide (the active ingredients of Relpax and Brintellix, respectively), and Relpax and Brintellix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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