Remodulin and Apixaban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Remodulin (treprostinil sodium) and Apixaban (apixaban). Common drug interactions include general physical health deterioration among females and septic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Remodulin and Apixaban. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Remodulin?

Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,843 Remodulin users. Check the latest studies of Remodulin.

What is Apixaban?

Apixaban has active ingredients of apixaban. It is often used in blood clots. eHealthMe is studying from 60,349 Apixaban users. Check the latest studies of Apixaban.

On Jul, 05, 2026

52 people who take Remodulin and Apixaban together, and have interactions are studied.

Remodulin and Apixaban drug interactions.

What are the common drug interactions of Remodulin and Apixaban, by gender? *:

female:

General physical health deterioration (weak health status)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Uterine haemorrhage (uterine bleeding)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Burning sensation
Chest pain
Dizziness
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Heart rate increased

male:

Septic shock (shock due to blood infection)
Cardiac failure
Back pain
Fluid retention (an abnormal accumulation of fluid in the blood)
Injection site erythema (redness at injection site)
Weight decreased
Hypotension (abnormally low blood pressure)
Abdominal discomfort
Cough
Device occlusion

What are the common drug interactions of Remodulin and Apixaban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Uterine haemorrhage (uterine bleeding)
Hyperthyroidism (over activity of the thyroid gland)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Thrombocytopenia (decrease of platelets in blood)
Weight decreased
General physical health deterioration (weak health status)
Headache (pain in head)
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Rhinovirus infection

20-29:

Fatigue (feeling of tiredness)
Headache (pain in head)
Hospitalisation
Nausea (feeling of having an urge to vomit)

30-39:

Dyspnoea (difficult or laboured respiration)
Hospitalisation
Nausea (feeling of having an urge to vomit)
Ascites (accumulation of fluid in the abdominal cavity)
Blood pressure decreased
Body temperature increased
Cardiac disorder
Cardiac failure
Death
Headache (pain in head)

40-49:

Septic shock (shock due to blood infection)
Back pain
Blood creatinine increased
Diarrhoea
Fluid overload (too much fluid in the blood)
Fluid retention (an abnormal accumulation of fluid in the blood)
Oedema peripheral (superficial swelling)
Oliguria (not enough urine)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

50-59:

Peripheral swelling
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Injection site discharge
Injection site exfoliation (removal of the oldest dead skin from injection site)
Injection site hypersensitivity
Injection site irritation
Abdominal discomfort
Abdominal pain
Anaemia (lack of blood)

60+:

Fluid retention (an abnormal accumulation of fluid in the blood)
Dyspnoea (difficult or laboured respiration)
Burning sensation
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Chest pain
Death
Dizziness
Abdominal discomfort
Heart rate increased
Hospitalisation

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 12 people, 23.08%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 7.69%
Migraine (headache): 4 people, 7.69%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 4 people, 7.69%
Pulmonary Thrombosis (scarring in the lungs): 3 people, 5.77%
Pain: 3 people, 5.77%
Nausea And Vomiting: 3 people, 5.77%
Nausea (feeling of having an urge to vomit): 3 people, 5.77%
Headache (pain in head): 3 people, 5.77%
Fever: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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