Remodulin and Ativan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Remodulin (treprostinil sodium) and Ativan (lorazepam). Common drug interactions include hyponatraemia among females and supraventricular tachycardia among males.
The phase IV clinical study analyzes what interactions people have when they take Remodulin and Ativan. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.
What is Remodulin?
Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,843 Remodulin users. Check the latest studies of Remodulin.
What is Ativan?
Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.
84 people who take Remodulin and Ativan together, and have interactions are studied.

What are the common drug interactions of Remodulin and Ativan, by gender? *:
female:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Presyncope
- Weight increased
- Hypoxia (low oxygen in tissues)
- Lung disorder (lung disease)
- Peripheral swelling
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Cardiac failure acute
- Dehydration (dryness resulting from the removal of water)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
male:
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Hypokalaemia (low potassium)
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Arthralgia (joint pain)
- Diarrhoea
- Dizziness
- Drug intolerance (drug sensitivity)
- Gout (uric acid crystals building up in the body)
- Hypophagia (reduced food intake)
- Malaise (a feeling of general discomfort or uneasiness)
What are the common drug interactions of Remodulin and Ativan, by age (0-1 to 60+)? *:
0-1:
- Oxygen saturation decreased
- Rhinovirus infection
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
2-9:
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Enterococcal infection
- Infusion site erythema (reddening of the skin at infusion site)
- Infusion site reaction
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Tracheostomy infection (infection of trachea surgical opening)
10-19:
- Abdominal pain
- Faecaloma (hard mass of fecal matter)
20-29:
- Psychotic disorder
- Agitation (state of anxiety or nervous excitement)
- Hypoxia (low oxygen in tissues)
- Loss of consciousness
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Syncope (loss of consciousness with an inability to maintain postural tone)
30-39:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
- Vomiting
- Blood pressure decreased
- Lung disorder (lung disease)
- Diarrhoea
- Pain in jaw
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Abdominal pain
40-49:
- Renal failure (kidney dysfunction)
- Cardiac failure congestive
- Gait disturbance
- Chest pain
- Acute myocardial infarction (acute heart attack)
- Abdominal pain
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Productive cough
- Oedema peripheral (superficial swelling)
50-59:
- Hypokalaemia (low potassium)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Chest pain
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Death
- Acetonaemia (acetone bodies in the blood)
- Blood magnesium decreased
- Brain natriuretic peptide increased
- Diabetic coma
60+:
- Hypotension (abnormally low blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Oedema peripheral (superficial swelling)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Vision blurred
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Blood pressure systolic decreased
- Cardiac failure
What are the existing conditions these people have? *
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 25 people, 29.76%
- Wheezing (a high-pitched whistling sound made while you breath): 6 people, 7.14%
- Pain: 6 people, 7.14%
- Oedema (fluid collection in tissue): 5 people, 5.95%
- Dyspnea (difficult or laboured breathing): 5 people, 5.95%
* Approximation only. Some reports may have incomplete information.
Do you take Remodulin and Ativan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Remodulin and Ativan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Remodulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ativan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Remodulin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ativan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on treprostinil sodium and lorazepam (the active ingredients of Remodulin and Ativan, respectively), and Remodulin and Ativan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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