Remodulin and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Remodulin (treprostinil sodium) and Codeine (codeine sulfate). Common drug interactions include fatigue among females and catheter site infection among males.

The phase IV clinical study analyzes what interactions people have when they take Remodulin and Codeine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Remodulin?

Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,843 Remodulin users. Check the latest studies of Remodulin.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

On Jul, 27, 2026

11 people who take Remodulin and Codeine together, and have interactions are studied.

Remodulin and Codeine drug interactions.

What are the common drug interactions of Remodulin and Codeine, by gender? *:

female:

Fatigue (feeling of tiredness)
Chest discomfort
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Arthralgia (joint pain)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Disease progression
Dyspnoea exertional (breathlessness or shortness of breath)

male:

Catheter site infection (infection at the site of insertion)
Fatigue (feeling of tiredness)
Coagulopathy (blood's ability to clot is impaired)
Infection
Abdominal discomfort
Abdominal distension
Anxiety
Asthenia (weakness)
Brain natriuretic peptide increased
Cardiac failure

What are the common drug interactions of Remodulin and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Catheter site infection (infection at the site of insertion)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Heart rate irregular
Infusion site erythema (reddening of the skin at infusion site)
Infusion site haemorrhage (bleeding from infusion site)
Infusion site swelling
Injection site reaction
Oedema (fluid collection in tissue)
Rash

10-19:

n/a

20-29:

n/a

30-39:

Activated partial thromboplastin time prolonged
Disease progression
General physical health deterioration (weak health status)
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Haemorrhage (bleeding)
Platelet count decreased
Red blood cell count decreased

40-49:

Abdominal discomfort
Abdominal distension
Alopecia (absence of hair from areas of the body)
Ascites (accumulation of fluid in the abdominal cavity)
Cardiac failure
Chest pain
Cough
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)

50-59:

n/a

60+:

Fatigue (feeling of tiredness)
Chest discomfort
Diarrhoea
Disease progression
Disturbance in attention
Dyspnoea exertional (breathlessness or shortness of breath)
Fall
Flatulence (flatus expelled through the anus)
Hypervolaemia (abnormally increased volume of blood)
Infusion site erythema (reddening of the skin at infusion site)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 36.36%
Sedation: 2 people, 18.18%
Right Ventricular Failure (right half of the heart fails to work): 2 people, 18.18%
Gastritis - Chronic (long lasting inflammation of stomach): 2 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 18.18%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 18.18%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 18.18%
Hypokalemia (low potassium): 2 people, 18.18%
Peripheral Swelling: 2 people, 18.18%
Asthma: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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