Renagel and Catapres-tts-1 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Catapres-tts-1 (clonidine). Common drug interactions include nephrogenic systemic fibrosis among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Catapres-tts-1. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Catapres-tts-1?

Catapres-tts-1 has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 2,047 Catapres-tts-1 users. Check the latest studies of Catapres-tts-1.

On Jul, 04, 2026

16 people who take Renagel and Catapres-tts-1 together, and have interactions are studied.

Renagel and Catapres-tts-1 drug interactions.

What are the common drug interactions of Renagel and Catapres-Tts-1, by gender? *:

female:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Laceration (tearing of soft body tissue)
Mobility decreased (ability to move is reduced)
Muscle fibrosis (fibrous muscle)
Muscle spasms (muscle contraction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Pleural effusion (water on the lungs)
Pneumonia

male:

Cardiac failure congestive
Erythema (redness of the skin)
Fabry's disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells)
Foot fracture
Infusion related reaction
Lymphoedema (localized fluid retention and tissue swelling)
Pain
Renal impairment (severely reduced kidney function)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Renagel and Catapres-Tts-1, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthralgia (joint pain)
Complex partial seizures (epileptic seizure)
Herpes simplex (herpes simplex is a common viral infection)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Pneumonia
Vomiting

30-39:

Cardiac failure congestive
Erythema (redness of the skin)
Fabry's disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells)
Foot fracture
Infusion related reaction
Lymphoedema (localized fluid retention and tissue swelling)
Pain
Renal impairment (severely reduced kidney function)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pleural effusion (water on the lungs)
Pneumonia
Respiration (transport of oxygen from the outside air to the cells within tissues)
Staphylococcal infection (an infection with staphylococcus bacteria)
Urinary tract infection
Vomiting
Weight decreased

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Dry skin
Emotional distress
Erythema (redness of the skin)
Excoriation (to tear or wear off the skin of)
Gait disturbance
Injury
Joint range of motion decreased (disease of joint movement)
Joint stiffness

60+:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Respiratory failure (inadequate gas exchange by the respiratory system)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)
Staphylococcal bacteraemia (a bacterial infection of blood)
Unresponsive to stimuli
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 18.75%
Nuclear Magnetic Resonance Imaging Brain: 3 people, 18.75%
Vaginal Infection: 2 people, 12.50%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 2 people, 12.50%
Blood Phosphorus Increased: 2 people, 12.50%
Pain: 1 person, 6.25%
Nausea And Vomiting: 1 person, 6.25%
Nausea (feeling of having an urge to vomit): 1 person, 6.25%
Medical Device Complication: 1 person, 6.25%
Itching: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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