Renagel and Exjade drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Exjade (deferasirox). Common drug interactions include death among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Exjade. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

On Jul, 12, 2026

15 people who take Renagel and Exjade together, and have interactions are studied.

What are the common drug interactions of Renagel and Exjade, by gender? *:

female:

Death
Abdominal pain
Acidosis (build-up of carbon dioxide in the blood)
Acute myocardial infarction (acute heart attack)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Body temperature increased
Cardiomyopathy (weakening of the heart muscle)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Diastolic dysfunction

male:

Asthenia (weakness)
Cardiac failure acute
Epistaxis (bleed from the nose)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoxia (low oxygen in tissues)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Melaena (the passage of black, tarry stools)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pyothorax (accumulation of pus in the pleural cavity)

What are the common drug interactions of Renagel and Exjade, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)

40-49:

Death

50-59:

n/a

60+:

Cardiac failure acute
Cellulitis (infection under the skin)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoxia (low oxygen in tissues)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Melaena (the passage of black, tarry stools)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pyothorax (accumulation of pus in the pleural cavity)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 6 people, 40.00%
Pain: 2 people, 13.33%
Nausea (feeling of having an urge to vomit): 2 people, 13.33%
Multiple Myeloma (cancer of the plasma cells): 2 people, 13.33%
Metastases To Bone (cancer spreads to bone): 2 people, 13.33%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
Spherocytic Anaemia (a type of anaemia with red blood cells that are shaped like spheres): 1 person, 6.67%
Renal Cell Carcinoma (a kidney cancer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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