Renagel and Lidocaine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Lidocaine (lidocaine). Common drug interactions include asthenia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Lidocaine. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Lidocaine?

Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 27,555 Lidocaine users. Check the latest studies of Lidocaine.

On Jul, 08, 2026

93 people who take Renagel and Lidocaine together, and have interactions are studied.

Renagel and Lidocaine drug interactions.

What are the common drug interactions of Renagel and Lidocaine, by gender? *:

female:

Asthenia (weakness)
Oedema peripheral (superficial swelling)
Dyspnoea (difficult or laboured respiration)
Muscular weakness (muscle weakness)
Injury
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Renal failure chronic (long lasting kidney dysfunction)

male:

Renal failure (kidney dysfunction)
Diarrhoea
Chest pain
Cholecystitis acute (rapid infection of gallbladder)
Arteriovenous fistula occlusion
Decreased appetite
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Gastroenteritis (inflammation of stomach and intestine)
Hypertension (high blood pressure)
Injury

What are the common drug interactions of Renagel and Lidocaine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arteriovenous fistula occlusion
Diarrhoea
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Gastroenteritis (inflammation of stomach and intestine)
Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
Graft loss (graft failure)
Thrombosis (formation of a blood clot inside a blood vessel)

20-29:

n/a

30-39:

Arthralgia (joint pain)
Atrophy (wasting away of a part of the body)
Dry skin
Exfoliative rash (scaly red generalized skin rash)
Gait disturbance
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

40-49:

Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Abdominal pain upper
Acute leukaemia (blood cancer)
Anaemia (lack of blood)
Arteriovenous fistula site complication
Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
Arteriovenous graft aneurysm
Back pain
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)

50-59:

Bone disorder
Dyspepsia (indigestion)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Jaw fracture
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Renal failure chronic (long lasting kidney dysfunction)
Tooth abscess (pus formation in tooth)
Urinary tract infection
Adrenal neoplasm (abnormal growth of adrenal gland)
Ankle fracture

60+:

Death
Anxiety
Stress
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Chest pain
Melaena (the passage of black, tarry stools)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cholecystitis acute (rapid infection of gallbladder)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 12.90%
Multiple Myeloma (cancer of the plasma cells): 11 people, 11.83%
Light Chain Analysis Increased: 11 people, 11.83%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 9 people, 9.68%
Neoplasm Malignant (cancer tumour): 8 people, 8.60%
High Blood Cholesterol: 7 people, 7.53%
Nausea And Vomiting: 7 people, 7.53%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 6.45%
Fever: 6 people, 6.45%
Headache (pain in head): 6 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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