Renagel and Repaglinide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Repaglinide (repaglinide). Common drug interactions include pulmonary embolism among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Repaglinide. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Repaglinide?

Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.

On Jul, 31, 2026

22 people who take Renagel and Repaglinide together, and have interactions are studied.

Renagel and Repaglinide drug interactions.

What are the common drug interactions of Renagel and Repaglinide, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Diarrhoea
Hypotension (abnormally low blood pressure)
Anaemia (lack of blood)
Cardiac failure congestive
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Circulatory collapse
Nausea (feeling of having an urge to vomit)
Pneumonia
Renal failure chronic (long lasting kidney dysfunction)

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Abdominal distension
Abdominal pain
Anaemia (lack of blood)
Angioplasty
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Blood pressure increased

What are the common drug interactions of Renagel and Repaglinide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Blood pressure increased
Cardiomegaly (increased size of heart than normal)
Constipation
Diarrhoea

50-59:

Circulatory collapse
Anaemia (lack of blood)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Dizziness
Hydrocephalus (water on the brain)
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Nephropathy (damage to or disease of a kidney)
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)

60+:

Pulmonary embolism (blockage of the main artery of the lung)
Alanine aminotransferase increased
Dysphagia (a condition in which swallowing is difficult or painful)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pneumonia
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.09%
Pain: 2 people, 9.09%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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