Renagel and Sulfamethoxazole and trimethoprim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Sulfamethoxazole and trimethoprim (sulfamethoxazole; trimethoprim). Common drug interactions include iron deficiency anaemia among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Sulfamethoxazole and trimethoprim. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Sulfamethoxazole and trimethoprim?

Sulfamethoxazole and trimethoprim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,645 Sulfamethoxazole and trimethoprim users. Check the latest studies of Sulfamethoxazole and trimethoprim.

On Jul, 18, 2026

18 people who take Renagel and Sulfamethoxazole and trimethoprim together, and have interactions are studied.

Renagel and Sulfamethoxazole and trimethoprim drug interactions.

What are the common drug interactions of Renagel and Sulfamethoxazole And Trimethoprim, by gender? *:

female:

Iron deficiency anaemia
Nephrogenic anaemia (anaemia due to kidney disease)
Upper respiratory tract inflammation
White blood cell count increased
Acetonaemic vomiting
Catheter related infection
Rash
Death
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
Disease recurrence

male:

Acute respiratory failure
Asthma
Hypertensive heart disease
Weight decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Pneumonia
Septic shock (shock due to blood infection)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety

What are the common drug interactions of Renagel and Sulfamethoxazole And Trimethoprim, by age (0-1 to 60+)? *:

0-1:

Acetonaemic vomiting
Catheter related infection
Rash
Cyclic vomiting syndrome (prolonged episodes of severe nausea, vomiting)
Disease recurrence
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Iron deficiency anaemia
Nephrogenic anaemia (anaemia due to kidney disease)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Colonic polyp (extra part of colon tissue grow in intestine)
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dizziness
Gastritis (inflammation of stomach)
Headache (pain in head)
Hypercapnia (too much smoke)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Irritable bowel syndrome

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Arthralgia (joint pain)
Bone density decreased
Gait disturbance
Malaise (a feeling of general discomfort or uneasiness)
Mobility decreased (ability to move is reduced)

50-59:

Diabetes mellitus inadequate control
Diabetic nephropathy (diabetic kidney disease)
Multiple injuries
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Renal failure chronic (long lasting kidney dysfunction)
Anaemia of chronic disease
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Hypertensive heart disease
Weight decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

Death
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Hepatomegaly (abnormal enlargement of the liver)
Multiple myeloma (cancer of the plasma cells)
Cellulitis (infection under the skin)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

What are the existing conditions these people have? *

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 5 people, 27.78%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 16.67%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 2 people, 11.11%
Hiv Infection: 2 people, 11.11%
Renal Artery Stenosis (narrowing of renal artery): 1 person, 5.56%
Pharyngeal Lesion: 1 person, 5.56%
Pain: 1 person, 5.56%
Osteomyelitis (infection of bone): 1 person, 5.56%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Renagel and Sulfamethoxazole and trimethoprim?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously