Renagel and Verelan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Verelan (verapamil hydrochloride). Common drug interactions include cerebrovascular stenosis among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Verelan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Verelan?

Verelan has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,377 Verelan users. Check the latest studies of Verelan.

On Jul, 07, 2026

13 people who take Renagel and Verelan together, and have interactions are studied.

What are the common drug interactions of Renagel and Verelan, by gender? *:

female:

Cerebrovascular stenosis (narrowing of brain blood vessels)
Gangrene (body tissue dies)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Peripheral vascular disorder
Psychotic disorder
Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular insufficiency (insufficient blood supply to brain)
Chronic kidney disease
Depression

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Scar
Skin hypertrophy (skin cells enlarges)
Skin induration (an abnormally hard spot or area on the skin)
Skin tightness
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain

What are the common drug interactions of Renagel and Verelan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Skin ulcer
Dysstasia (difficulty in standing)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Abasia (inability to walk)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Balance disorder
Burning sensation

50-59:

Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Balance disorder
Emotional distress
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gait disturbance
General physical health deterioration (weak health status)
Hypoaesthesia (reduced sense of touch or sensation)
Joint range of motion decreased (disease of joint movement)

60+:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Pain: 6 people, 46.15%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 5 people, 38.46%
Blood Phosphorus Increased: 5 people, 38.46%
Nuclear Magnetic Resonance Imaging Abdominal: 5 people, 38.46%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 15.38%
Diabetes: 2 people, 15.38%
Exostosis (formation of new bone on the surface of a bone): 2 people, 15.38%
Anaemia (lack of blood): 2 people, 15.38%
Iron Deficiency: 1 person, 7.69%
Indigestion: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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