Renvela and Pentoxifylline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renvela (sevelamer carbonate) and Pentoxifylline (pentoxifylline). Common drug interactions include renal failure among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Renvela and Pentoxifylline. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Renvela?

Renvela has active ingredients of sevelamer carbonate. eHealthMe is studying from 10,923 Renvela users. Check the latest studies of Renvela.

What is Pentoxifylline?

Pentoxifylline has active ingredients of pentoxifylline. eHealthMe is studying from 5,997 Pentoxifylline users. Check the latest studies of Pentoxifylline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

21 people who take Renvela and Pentoxifylline together, and have interactions are studied.

Renvela and Pentoxifylline drug interactions.

What are the common drug interactions of Renvela and Pentoxifylline, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Decreased activity

male:

Renal failure (kidney dysfunction)
Acute respiratory failure
Brain contusion (a form of traumatic brain injury)
Brain injury
Brain midline shift
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Eye pain
Fall
Head injury
Headache (pain in head)

What are the common drug interactions of Renvela and Pentoxifylline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Fatigue (feeling of tiredness)
Pain
Quality of life decreased
Renal failure (kidney dysfunction)
Renal transplant

40-49:

Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Fatigue (feeling of tiredness)
Pain
Quality of life decreased
Renal transplant
Agitation (state of anxiety or nervous excitement)

50-59:

Abdominal distension
Diarrhoea
Nausea (feeling of having an urge to vomit)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Vomiting

60+:

Renal failure (kidney dysfunction)
Chronic kidney disease
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dehydration (dryness resulting from the removal of water)
Food poisoning (poison in food)
Gastroenteritis (inflammation of stomach and intestine)
Renal disorder (kidney disease)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 33.33%
High Blood Pressure: 5 people, 23.81%
Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 19.05%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 4 people, 19.05%
Hyperkalemia (damage to or disease of the kidney): 3 people, 14.29%
Hiv Infection: 3 people, 14.29%
Cough: 2 people, 9.52%
Arterial Disorder: 2 people, 9.52%
Blood Phosphorus Increased: 2 people, 9.52%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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