Repatha and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Acyclovir (acyclovir). Common drug interactions include malaise among females and hypokalaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Acyclovir. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,258 Repatha users. Check the latest studies of Repatha.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

eHealtheMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 13, 2026

42 people who take Repatha and Acyclovir together, and have interactions are studied.

Repatha and Acyclovir drug interactions.

What are the common drug interactions of Repatha and Acyclovir, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Menopausal symptoms
Mitral valve incompetence (inefficient heart valve)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Osteopenia (a condition where bone mineral density is lower than normal)
Pancreatic carcinoma (pancreatic cancer)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Peripheral swelling

male:

Hypokalaemia (low potassium)
Arthralgia (joint pain)
Balance disorder
Blood creatinine increased
Bone density decreased
Chronic kidney disease
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Fracture
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)

What are the common drug interactions of Repatha and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypokalaemia (low potassium)
Anaemia (lack of blood)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Blood creatinine increased
Bone density decreased
Chronic kidney disease
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Fracture

60+:

Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure increased
Anaphylactic reaction (serious allergic reaction)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Cardiac arrest
Coronavirus test positive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 17 people, 40.48%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 11.90%
Atherosclerosis (disorder of the arteries): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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