Repatha and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Morphine sulfate (morphine sulfate). Common drug interactions include urticaria among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Morphine sulfate. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.

On Jul, 08, 2026

23 people who take Repatha and Morphine sulfate together, and have interactions are studied.

Repatha and Morphine sulfate drug interactions.

What are the common drug interactions of Repatha and Morphine Sulfate, by gender? *:

female:

Urticaria (rash of round, red welts on the skin that itch intensely)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Weight decreased
Drug hypersensitivity
Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Asthma
Blood pressure systolic increased
Body temperature decreased

male:

Headache (pain in head)
Chest pain
Chronic kidney disease
Pyrexia (fever)
Renal failure (kidney dysfunction)
Skin cancer
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Burning sensation
Gastritis (inflammation of stomach)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Repatha and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Asthma
Blood pressure systolic increased
Body temperature decreased
Contusion (a type of hematoma of tissue in which capillaries)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

50-59:

Burning sensation
Headache (pain in head)
Abdominal pain
Adverse event
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)
Cardiac murmur (an heart sound in valve abnormality)
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)

60+:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Urticaria (rash of round, red welts on the skin that itch intensely)
Eye pain
Eyelid irritation
Gastrointestinal hypomotility (less activity of the intestinal tract)
Haematoma (collection of blood outside the blood vessels)
Lip and/or oral cavity cancer (cancer of lip or mouth)
Neck mass (mass in neck)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 17.39%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 17.39%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 13.04%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.70%
Migraine (headache): 2 people, 8.70%
Immunodeficiency Common Variable: 2 people, 8.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
Diabetes: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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