Repatha and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Oxycontin (oxycodone hydrochloride). Common drug interactions include dyspnoea among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Oxycontin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.

On Jul, 08, 2026

19 people who take Repatha and Oxycontin together, and have interactions are studied.

Repatha and Oxycontin drug interactions.

What are the common drug interactions of Repatha and Oxycontin, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Asthenia (weakness)
Chest discomfort
Cold sweat
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness

male:

Arthralgia (joint pain)
Chest discomfort
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Neoplasm malignant (cancer tumour)
Productive cough
Pulmonary eosinophilia (increase in the number of eosinophiles in the blood causeing lung infection)
Rash
Skin discolouration (change of skin colour)

What are the common drug interactions of Repatha and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Rash
Skin discolouration (change of skin colour)

50-59:

Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Asthenia (weakness)
Chest discomfort
Cold sweat
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dry skin

60+:

Chest discomfort
Death
Injection site pain
Insomnia (sleeplessness)
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Mumps (a virus that can lead to swelling and pain in the salivary glands, along with fever, loss of appetite, and fatigue)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pneumonia
Productive cough
Pulmonary eosinophilia (increase in the number of eosinophiles in the blood causeing lung infection)

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 3 people, 15.79%
Stress And Anxiety: 2 people, 10.53%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.53%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 10.53%
Dyslipidaemia (abnormal amount of lipids): 2 people, 10.53%
Pancreatitis Acute (sudden inflammation of pancreas): 1 person, 5.26%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%
Diabetes: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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