Repatha and Paroxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Paroxetine (paroxetine hydrochloride). Common drug interactions include cough among females and epilepsy among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Paroxetine. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Paroxetine?

Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 65,088 Paroxetine users. Check the latest studies of Paroxetine.

On Jul, 19, 2026

52 people who take Repatha and Paroxetine together, and have interactions are studied.

Repatha and Paroxetine drug interactions.

What are the common drug interactions of Repatha and Paroxetine, by gender? *:

female:

Cough
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Pruritus (severe itching of the skin)
Chills (felling of cold)
Sneezing
Skin disorder (skin disease)
Arthralgia (joint pain)
Lymphadenopathy (disease or enlargement of lymph nodes)
Multiple allergies (allergy to multiple agents)

male:

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Injection site pain
Nervousness
Renal injury (kidney injury)
Somnolence (a state of near-sleep, a strong desire for sleep)
Surgery
Injection site swelling
Death
Decreased appetite
Depressed mood

What are the common drug interactions of Repatha and Paroxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depressed mood
Facial paralysis (loss of function of face muscle)
Nervousness

50-59:

Arthralgia (joint pain)
Chest pain
Lower limb fracture
Thrombosis (formation of a blood clot inside a blood vessel)
Abdominal distension
Abdominal pain upper
Flatulence (flatus expelled through the anus)
Intra-abdominal pressure increased
Oesophageal spasm (contraction of oesophagus)

60+:

Cough
Oropharyngeal pain
Alopecia (absence of hair from areas of the body)
Nephrolithiasis (calculi in the kidneys)
Arthralgia (joint pain)
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Death
Drug ineffective
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 26.92%
Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 17.31%
Depression: 4 people, 7.69%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 5.77%
Back Pain: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and Paroxetine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously