Repatha and Ranitidine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Ranitidine hydrochloride (ranitidine hydrochloride). Common drug interactions include anaemia among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Ranitidine hydrochloride. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Ranitidine hydrochloride?

Ranitidine hydrochloride has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 76,413 Ranitidine hydrochloride users. Check the latest studies of Ranitidine hydrochloride.



On Jul, 08, 2026

26 people who take Repatha and Ranitidine hydrochloride together, and have interactions are studied.

Repatha and Ranitidine hydrochloride drug interactions.

What are the common drug interactions of Repatha and Ranitidine Hydrochloride, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Chronic kidney disease
  4. Depression
  5. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  6. Fear of disease
  7. Gallbladder disorder
  8. Iron deficiency
  9. Irritable bowel syndrome
  10. Mania (a state of abnormally elevated or irritable mood)

male:

  1. Constipation
  2. Malignant neoplasm progression (cancer tumour came back)
  3. Drug ineffective
  4. Drug intolerance (drug sensitivity)
  5. Heart valve replacement
  6. Muscle spasms (muscle contraction)
  7. Pruritus (severe itching of the skin)
  8. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  9. Anaphylactic reaction (serious allergic reaction)
  10. Eye swelling

What are the common drug interactions of Repatha and Ranitidine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Constipation
  2. Malignant neoplasm progression (cancer tumour came back)
  3. Muscle spasms (muscle contraction)
  4. Anaemia (lack of blood)
  5. Anxiety
  6. Chronic kidney disease
  7. Depression
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Fear of disease
  10. Gallbladder disorder

60+:

  1. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  2. Influenza like illness
  3. Anaphylactic reaction (serious allergic reaction)
  4. Eye swelling
  5. Lacrimation increased
  6. Peripheral swelling
  7. Alopecia (absence of hair from areas of the body)
  8. Dementia (madness)
  9. Drug intolerance (drug sensitivity)
  10. Heart valve replacement

What are the existing conditions these people have? *

  1. Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 23.08%
  2. High Blood Pressure: 5 people, 19.23%
  3. Nausea (feeling of having an urge to vomit): 5 people, 19.23%
  4. Weight Decreased: 4 people, 15.38%
  5. Urinary Tract Infection: 4 people, 15.38%
  6. Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 4 people, 15.38%
  7. Blood Pressure Abnormal: 4 people, 15.38%
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 4 people, 15.38%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 15.38%
  10. Gastric Ulcer (stomach ulcer): 4 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and Ranitidine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Repatha and Ranitidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ranitidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repatha and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ranitidine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab and ranitidine hydrochloride (the active ingredients of Repatha and Ranitidine hydrochloride, respectively), and Repatha and Ranitidine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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