Requip and Firazyr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Requip (ropinirole hydrochloride) and Firazyr (icatibant acetate). Common drug interactions include hereditary angioedema among females and laryngeal oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Requip and Firazyr. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Firazyr?

Firazyr has active ingredients of icatibant acetate. eHealthMe is studying from 5,650 Firazyr users. Check the latest studies of Firazyr.



On Aug, 02, 2026

14 people who take Requip and Firazyr together, and have interactions are studied.

Requip and Firazyr drug interactions.

What are the common drug interactions of Requip and Firazyr, by gender? *:

female:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Erythema (redness of the skin)
  3. Eye swelling
  4. Foot fracture
  5. Hospitalisation
  6. Localised oedema (fluid retention in a particular part of the body)
  7. Migraine (headache)
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Nausea (feeling of having an urge to vomit)
  10. Oxygen saturation decreased

male:

  1. Laryngeal oedema (swelling of larynx)

What are the common drug interactions of Requip and Firazyr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Eye swelling
  3. Hereditary angioedema (recurrent episodes of severe swelling)
  4. Laryngeal oedema (swelling of larynx)
  5. Localised oedema (fluid retention in a particular part of the body)
  6. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  7. Stress
  8. Swelling face

40-49:

  1. Erythema (redness of the skin)
  2. Foot fracture
  3. Migraine (headache)
  4. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  5. Nausea (feeling of having an urge to vomit)
  6. Pain in extremity
  7. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  8. Pyrexia (fever)
  9. Swelling
  10. Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hereditary angioedema (recurrent episodes of severe swelling)
  3. Oxygen saturation decreased
  4. Pneumonia
  5. Respiratory failure (inadequate gas exchange by the respiratory system)
  6. Stridor

60+:

n/a

What are the existing conditions these people have? *

  1. Hereditary Angioedema (recurrent episodes of severe swelling): 14 people, 100.00%
  2. Vitamin B12 Deficiency: 1 person, 7.14%
  3. Sleep Disorder: 1 person, 7.14%
  4. Migraine (headache): 1 person, 7.14%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
  6. Hypersensitivity: 1 person, 7.14%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.14%
  8. Birth Control: 1 person, 7.14%
  9. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.14%
  10. Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and Firazyr?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Requip and Firazyr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Firazyr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Requip and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Firazyr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride and icatibant acetate (the active ingredients of Requip and Firazyr, respectively), and Requip and Firazyr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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