Requip and Magnesium oxide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Requip (ropinirole hydrochloride) and Magnesium oxide (magnesium). Common drug interactions include vitamin d deficiency among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Requip and Magnesium oxide. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Magnesium oxide?

Magnesium oxide has active ingredients of magnesium. It is often used in migraine. eHealthMe is studying from 19,022 Magnesium oxide users. Check the latest studies of Magnesium oxide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

90 people who take Requip and Magnesium oxide together, and have interactions are studied.

Requip and Magnesium oxide drug interactions.

What are the common drug interactions of Requip and Magnesium Oxide, by gender? *:

female:

Vitamin d deficiency
Anxiety
Cellulitis (infection under the skin)
Lung disorder (lung disease)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Urinary tract infection
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Blood creatinine increased
Chest pain
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Ejection fraction decreased (systolic heart failure)
Epistaxis (bleed from the nose)
Eye inflammation
Hypoacusis (loss of hearing)
Hypotension (abnormally low blood pressure)
Loss of consciousness

What are the common drug interactions of Requip and Magnesium Oxide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Haemoglobin decreased
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Diarrhoea

30-39:

n/a

40-49:

Pain
Anxiety
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cellulitis (infection under the skin)
Chest pain
Cystitis (inflammation of the wall of the bladder)
Fatigue (feeling of tiredness)
Gastric infection (infection of stomach)
Headache (pain in head)

50-59:

Sleep disorder
Weight decreased
Abnormal behaviour
Abscess limb (limb infection)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anaemia (lack of blood)
Anal abscess
Balance disorder
Cardiac disorder
Cellulitis (infection under the skin)

60+:

Acute respiratory failure
Pneumonia
Dehydration (dryness resulting from the removal of water)
Ejection fraction decreased (systolic heart failure)
Hypotension (abnormally low blood pressure)
Loss of consciousness
Nasal inflammation (inflammation of nose)
Pulmonary oedema (fluid accumulation in the lungs)
Rash
Swelling

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 14.44%
Pain: 13 people, 14.44%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 14.44%
Depression: 13 people, 14.44%
Parkinson's Disease: 11 people, 12.22%
Constipation: 10 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 11.11%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 8.89%
Stress And Anxiety: 8 people, 8.89%
Nausea (feeling of having an urge to vomit): 7 people, 7.78%

* Approximation only. Some reports may have incomplete information.

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