Requip and Methylprednisolone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Requip (ropinirole hydrochloride) and Methylprednisolone (methylprednisolone). Common drug interactions include breast cellulitis among females and hypertension among males.
The phase IV clinical study analyzes what interactions people have when they take Requip and Methylprednisolone. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.
What is Requip?
Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.
What is Methylprednisolone?
Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
45 people who take Requip and Methylprednisolone together, and have interactions are studied.

What are the common drug interactions of Requip and Methylprednisolone, by gender? *:
female:
- Breast cellulitis (spreading, acute inflammation of beast skin)
- Cardiac arrest
- Cardiac failure congestive
- Diarrhoea haemorrhagic (bloody diarrhoea)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Erythema (redness of the skin)
- Faecal incontinence (a lack of control over passing stool)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Flatulence (flatus expelled through the anus)
- Galactorrhoea (secretion of breast milk in men)
male:
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
- Blood glucose increased
- Blood triglycerides increased
- Cardiac valve disease (heart valve disease)
- Chest discomfort
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Colitis (inflammation of colon)
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
What are the common drug interactions of Requip and Methylprednisolone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Arthralgia (joint pain)
- Balance disorder
- Bladder spasm
- Breast abscess
- Breast cellulitis (spreading, acute inflammation of beast skin)
- Breast tenderness
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
40-49:
- Chronic kidney disease
- Anxiety
- Abdominal distension
- Abdominal pain
- Abdominal pain upper
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Balance disorder
- Breast abscess
- Breast cellulitis (spreading, acute inflammation of beast skin)
- Chest pain
50-59:
- Iritis (painful inflammation of the iris of the eye)
- Uveitis (inflammation of the uvea)
- Blindness unilateral
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dehydration (dryness resulting from the removal of water)
- Haematocrit decreased
- Haemoglobin decreased
- Hyperchlorhydria (gastric acid levels are higher in stomach)
- Pain
- Peptic ulcer
60+:
- Haematoma (collection of blood outside the blood vessels)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Hypertension (high blood pressure)
- Pain
- Abdominal pain upper
- Arthralgia (joint pain)
- Bradycardia (abnormally slow heart action)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chest pain
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Pain: 21 people, 46.67%
- Stress And Anxiety: 11 people, 24.44%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 22.22%
- Depression: 8 people, 17.78%
- Insomnia (sleeplessness): 7 people, 15.56%
- High Blood Pressure: 7 people, 15.56%
- Asthma: 6 people, 13.33%
- Nausea (feeling of having an urge to vomit): 6 people, 13.33%
- Nausea And Vomiting: 5 people, 11.11%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 11.11%
* Approximation only. Some reports may have incomplete information.
Do you take Requip and Methylprednisolone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Requip (22,950 reports)
- Methylprednisolone (59,645 reports)
Browse all drug interactions of Requip and Methylprednisolone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Requip:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Methylprednisolone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Requip and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methylprednisolone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ropinirole hydrochloride and methylprednisolone (the active ingredients of Requip and Methylprednisolone, respectively), and Requip and Methylprednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Metoprolol Succinate cause Organ Failure? - 19 seconds ago
- Could Propranolol Hydrochloride cause Hypovolaemic Shock? - 21 seconds ago
- Could Norplant cause Oedema Upper Limb? - 21 seconds ago
- Could Entresto cause Troponin I Increased? - 21 seconds ago
- Could Topotecan cause Abdominal Pain Upper? - 24 seconds ago
- Could Tolterodine cause Hypotension? - 29 seconds ago
- Drug interactions of Ammonium Lactate and Rosuvastatin Calcium - 32 seconds ago
- Could Midodrine Hydrochloride cause Hair Loss? - 33 seconds ago
- Could Estradiol cause Eye Haemorrhage? - 35 seconds ago
- Could Valsartan cause Acute Hepatic Failure? - 38 seconds ago