Restasis and Apriso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Apriso (mesalamine). Common drug interactions include asthenia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Apriso. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

On Jul, 25, 2026

32 people who take Restasis and Apriso together, and have interactions are studied.

What are the common drug interactions of Restasis and Apriso, by gender? *:

female:

Asthenia (weakness)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Abnormal faeces (abnormal stool)
Alopecia (absence of hair from areas of the body)
Anxiety
Arthralgia (joint pain)
Chills (felling of cold)
Drug hypersensitivity
Fatigue (feeling of tiredness)

male:

Fatigue (feeling of tiredness)
Cardiac failure congestive
Injection site pain
Instillation site lacrimation
Malaise (a feeling of general discomfort or uneasiness)
Post procedural sepsis
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Viral infection
Weight increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Restasis and Apriso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Injection site pain

40-49:

Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

50-59:

Asthenia (weakness)
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Abnormal faeces (abnormal stool)
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Hypophagia (reduced food intake)
Intestinal resection
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

60+:

Arthralgia (joint pain)
Drug hypersensitivity
Diarrhoea
Drug effect delayed
Dyspnoea (difficult or laboured respiration)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Gait disturbance
General symptom

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 31.25%
High Blood Pressure: 8 people, 25.00%
High Blood Cholesterol: 7 people, 21.88%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 21.88%
Asthma: 5 people, 15.62%
Cystitis Interstitial (unknown cause characterized by bladder pain): 5 people, 15.62%
Menopause (end of monthly cycles in women): 4 people, 12.50%
Eye Disorder: 4 people, 12.50%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 12.50%
Hypersensitivity: 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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