Restasis and Atacand drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Restasis (cyclosporine) and Atacand (candesartan cilexetil). Common drug interactions include tachycardia among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Restasis and Atacand. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
What is Atacand?
Atacand has active ingredients of candesartan cilexetil. It is often used in high blood pressure. eHealthMe is studying from 22,473 Atacand users. Check the latest studies of Atacand.
40 people who take Restasis and Atacand together, and have interactions are studied.

What are the common drug interactions of Restasis and Atacand, by gender? *:
female:
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Chronic kidney disease
- Dizziness
- Gait disturbance
- Oedema peripheral (superficial swelling)
- Renal failure (kidney dysfunction)
- Swelling
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Eye irritation
- Heart rate increased
male:
- Anaemia (lack of blood)
- Eye irritation
- Oedema peripheral (superficial swelling)
- Pyrexia (fever)
What are the common drug interactions of Restasis and Atacand, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Nausea (feeling of having an urge to vomit)
- Neoplasm malignant (cancer tumour)
50-59:
- Drug ineffective
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Foreign body sensation in eyes (feeling of something in eye)
- Vulvovaginal mycotic infection (vulvovaginal fungal infection)
60+:
- Oedema peripheral (superficial swelling)
- Pain in extremity
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal discomfort
- Asthma
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dry throat
- Hearing impaired
- Muscle spasms (muscle contraction)
- Myalgia (muscle pain)
What are the existing conditions these people have? *
- High Blood Cholesterol: 8 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.50%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 12.50%
- Asthma: 4 people, 10.00%
- Insomnia (sleeplessness): 4 people, 10.00%
- Pain: 3 people, 7.50%
- Cardiac Disorder: 3 people, 7.50%
- Gastric Ph Decreased: 3 people, 7.50%
- Urinary Tract Infection: 2 people, 5.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Restasis and Atacand?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Restasis and Atacand:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Atacand:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Atacand and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cyclosporine and candesartan cilexetil (the active ingredients of Restasis and Atacand, respectively), and Restasis and Atacand (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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