Restasis and Cleocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Cleocin (clindamycin phosphate). Common drug interactions include osteomyelitis among females and abscess neck among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Cleocin. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

On Jul, 29, 2026

52 people who take Restasis and Cleocin together, and have interactions are studied.

What are the common drug interactions of Restasis and Cleocin, by gender? *:

female:

Osteomyelitis (infection of bone)
Renal failure chronic (long lasting kidney dysfunction)
Spinal compression fracture (fracture due to spinal compression on bone)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hypokalaemia (low potassium)
Osteonecrosis of jaw (death of bone of jaw)
Joint dislocation (a joint position is changed from normal position)
Neuropathy peripheral (surface nerve damage)
Nausea (feeling of having an urge to vomit)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

male:

Abscess neck (neck abscesses)
Addison's disease (addison's disease, a hormonal disorder disease)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone disorder
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast haematoma (blood-filled swelling in the breast)
Cardiac arrest
Cardiac disorder

What are the common drug interactions of Restasis and Cleocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess (pus)
Anaemia of chronic disease
Anxiety
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood glucose increased
Blood pressure fluctuation

20-29:

Abscess (pus)
Anaemia of chronic disease
Anxiety
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood urea increased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

30-39:

Diarrhoea
Headache (pain in head)
Rash
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)
Abdominal pain
Abdominal tenderness
Appetite disorder (abnormal eating habits)

40-49:

Catheter site erythema (redness of skin at catheter site)
Chills (felling of cold)
Cough
Erythema (redness of the skin)
Lip swelling
Peripheral swelling
Pneumonia
Pyrexia (fever)
Skin exfoliation (removal of the oldest dead skin cells)
Swelling

50-59:

Bone disorder
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac arrest
Cardiac disorder
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Coagulopathy (blood's ability to clot is impaired)

60+:

Cellulitis (infection under the skin)
Anaemia of chronic disease
Osteomyelitis (infection of bone)
Pain
Pyrexia (fever)
Renal failure chronic (long lasting kidney dysfunction)
Spinal compression fracture (fracture due to spinal compression on bone)
Urinary tract infection
Dizziness
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 19.23%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 10 people, 19.23%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 11.54%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 5 people, 9.62%
Immunodeficiency Common Variable: 4 people, 7.69%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 7.69%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 5.77%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 3 people, 5.77%
Pain: 3 people, 5.77%
Nausea (feeling of having an urge to vomit): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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