Restasis and Daypro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Restasis (cyclosporine) and Daypro (oxaprozin). Common drug interactions include atrial flutter among females and eye irritation among males.
The phase IV clinical study analyzes what interactions people have when they take Restasis and Daypro. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
What is Daypro?
Daypro has active ingredients of oxaprozin. It is often used in osteoarthritis. eHealthMe is studying from 2,883 Daypro users. Check the latest studies of Daypro.
16 people who take Restasis and Daypro together, and have interactions are studied.

What are the common drug interactions of Restasis and Daypro, by gender? *:
female:
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Back pain
- Blindness unilateral
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood potassium decreased
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Cardiac failure congestive
- Cataract (clouding of the lens inside the eye)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Congestive cardiomyopathy (weakening of heart muscle)
male:
- Eye irritation
- Eye pruritus (eye itching)
What are the common drug interactions of Restasis and Daypro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
50-59:
- Angiomyolipoma (most common benign tumour of the kidney)
- Anxiety
- Asthenia (weakness)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Back pain
- Blindness unilateral
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Blood potassium decreased
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
- Cardiac failure congestive
60+:
- Blood pressure decreased
- Constipation
- Epistaxis (bleed from the nose)
- Flatulence (flatus expelled through the anus)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Insomnia (sleeplessness)
- Pneumonia
- Shoulder operation
- Wound infection
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 25.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 18.75%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 18.75%
- Diabetes: 3 people, 18.75%
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 12.50%
- Infection: 2 people, 12.50%
- Blood Pressure Abnormal: 2 people, 12.50%
- Dyspnea (difficult or laboured breathing): 2 people, 12.50%
- Eye Pruritus (eye itching): 2 people, 12.50%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Restasis and Daypro?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Restasis and Daypro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Daypro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Daypro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cyclosporine and oxaprozin (the active ingredients of Restasis and Daypro, respectively), and Restasis and Daypro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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