Restasis and Ester c drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Ester c (l-ascorbic acid). Common drug interactions include drug ineffective among females and infusion site haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Ester c. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Ester c?

Ester c has active ingredients of l-ascorbic acid. eHealthMe is studying from 306 Ester c users. Check the latest studies of Ester c.



On Jul, 18, 2026

13 people who take Restasis and Ester c together, and have interactions are studied.

Restasis and Ester c drug interactions.

What are the common drug interactions of Restasis and Ester C, by gender? *:

female:

  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Vision blurred
  4. Abdominal pain upper
  5. Anaemia (lack of blood)
  6. Bell's palsy (facial paralysis)
  7. Breast mass
  8. Diarrhoea
  9. Dizziness
  10. Eye pain

male:

  1. Infusion site haemorrhage (bleeding from infusion site)
  2. Fatigue (feeling of tiredness)
  3. Discomfort
  4. Nausea (feeling of having an urge to vomit)
  5. Oral infection
  6. Headache (pain in head)
  7. Infusion site swelling
  8. Cough
  9. Infusion related reaction
  10. Migraine (headache)

What are the common drug interactions of Restasis and Ester C, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Breast mass
  3. Dizziness
  4. Drug ineffective
  5. Eye pain
  6. Metamorphopsia (a type of distorted vision in which a grid of straight lines appears wavy and parts of the grid may appear blank)
  7. Photophobia (extreme sensitivity to light)
  8. Urinary tract infection
  9. Vision blurred

60+:

  1. Abdominal pain upper
  2. Anaemia (lack of blood)
  3. Sneezing
  4. Vision blurred
  5. Vomiting
  6. Bell's palsy (facial paralysis)
  7. Diarrhoea
  8. Eyelid ptosis (falling of the upper or lower eyelid)
  9. Full blood count decreased
  10. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 4 people, 30.77%
  2. Neuralgia (pain in one or more nerves): 2 people, 15.38%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.69%
  4. Stress And Anxiety: 1 person, 7.69%
  5. Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 1 person, 7.69%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%
  7. Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%
  8. Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 7.69%
  9. Pain: 1 person, 7.69%
  10. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and Ester c?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Restasis and Ester c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ester c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Restasis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ester c and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and l-ascorbic acid (the active ingredients of Restasis and Ester c, respectively), and Restasis and Ester c (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: