Restasis and Farxiga drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Restasis (cyclosporine) and Farxiga (dapagliflozin). Common drug interactions include abscess among females and cough among males.
The phase IV clinical study analyzes what interactions people have when they take Restasis and Farxiga. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
What is Farxiga?
Farxiga has active ingredients of dapagliflozin. It is often used in diabetes. eHealthMe is studying from 18,798 Farxiga users. Check the latest studies of Farxiga.
38 people who take Restasis and Farxiga together, and have interactions are studied.

What are the common drug interactions of Restasis and Farxiga, by gender? *:
female:
- Abscess (pus)
- Abscess limb (limb infection)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Perirectal abscess
- Rectal abscess (pus in rectum)
- Haemolytic anaemia (anaemia due to haemolysis)
- Malignant neoplasm of islets of langerhans (cancer tumour of pancreas)
- Thyroid cancer
- Weight decreased
- Cartilage injury
male:
- Cough
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Nasopharyngitis (inflammation of the nasopharynx)
- Parkinsonian gait (gait exhibited by patients suffering from parkinson's disease)
- Peripheral swelling
- Sneezing
- Swelling face
- Asthenia (weakness)
- Blood pressure decreased
- Dizziness
What are the common drug interactions of Restasis and Farxiga, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Haemolytic anaemia (anaemia due to haemolysis)
- Malignant neoplasm of islets of langerhans (cancer tumour of pancreas)
- Thyroid cancer
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Visual acuity reduced (reduced clearness of vision)
50-59:
- Disease recurrence
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Dry mouth
60+:
- Cough
- Tremor (trembling or shaking movements in one or more parts of your body)
- Rectal abscess (pus in rectum)
- Back pain
- Cardiac disorder
- Dizziness
- Dysstasia (difficulty in standing)
- Fatigue (feeling of tiredness)
- Hallucination (an experience involving the perception of something not present)
- Nasopharyngitis (inflammation of the nasopharynx)
What are the existing conditions these people have? *
- Parkinson's Disease: 6 people, 15.79%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 15.79%
- Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 4 people, 10.53%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 10.53%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 7.89%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.89%
- Type 2 Diabetes: 2 people, 5.26%
- Osteoporosis (bones weak and more likely to break): 2 people, 5.26%
- Carcinoid Tumor: 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Restasis and Farxiga?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Restasis and Farxiga:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Farxiga:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Farxiga and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cyclosporine and dapagliflozin (the active ingredients of Restasis and Farxiga, respectively), and Restasis and Farxiga (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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