Restasis and Gliclazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Gliclazide (gliclazide). Common drug interactions include epilepsy among females and mental disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Gliclazide. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

28 people who take Restasis and Gliclazide together, and have interactions are studied.

Restasis and Gliclazide drug interactions.

What are the common drug interactions of Restasis and Gliclazide, by gender? *:

female:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  2. Staphylococcal infection (an infection with staphylococcus bacteria)
  3. Acne (skin problems that cause pimples)
  4. Alopecia (absence of hair from areas of the body)
  5. Disability
  6. Fall
  7. Hepatic steatosis (fatty liver disease)
  8. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Weight decreased

male:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Schizoaffective disorder (a mental disorder characterized by disordered thought)
  3. Asthenia (weakness)
  4. Death
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Gait disturbance
  8. Lung cancer metastatic (lung cancer spreads to other parts)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Schizoaffective disorder depressive type (mental illness featuring schizophrenia and a mood disorder)

What are the common drug interactions of Restasis and Gliclazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  2. Staphylococcal infection (an infection with staphylococcus bacteria)

40-49:

  1. Bladder pain
  2. Decreased appetite
  3. Hot flush (sudden feelings of heat)
  4. Night sweats (sweating in night)
  5. Weight decreased

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Death
  3. Cardiac flutter (abnormal heart rhythm)
  4. Chest pain
  5. Dysgeusia (disorder of the sense of taste)
  6. Lip swelling
  7. Lung disorder (lung disease)
  8. Oedema (fluid collection in tissue)
  9. Pleural effusion (water on the lungs)
  10. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 71.43%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 53.57%
  3. Ocular Pemphigoid (inflammatory autoimmune disorder characterized by blistering lesions that affect mucous membrane covering of eye): 4 people, 14.29%
  4. Rashes (redness): 3 people, 10.71%
  5. Migraine (headache): 2 people, 7.14%
  6. Drowsiness: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and Gliclazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Restasis and Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Restasis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gliclazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and gliclazide (the active ingredients of Restasis and Gliclazide, respectively), and Restasis and Gliclazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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