Restasis and Humulin n drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Humulin n (insulin susp isophane recombinant human). Common drug interactions include arthralgia among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Humulin n. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Humulin n?

Humulin n has active ingredients of insulin susp isophane recombinant human. It is often used in diabetes. eHealthMe is studying from 9,878 Humulin n users. Check the latest studies of Humulin n.



On Jul, 16, 2026

15 people who take Restasis and Humulin n together, and have interactions are studied.

Restasis and Humulin n drug interactions.

What are the common drug interactions of Restasis and Humulin N, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Exostosis (formation of new bone on the surface of a bone)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Visual acuity reduced (reduced clearness of vision)
  7. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  8. Drug ineffective
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Spinal osteoarthritis (joint cartilage loss in spine)

male:

  1. Hypertension (high blood pressure)
  2. Renal disorder (kidney disease)
  3. Gait disturbance
  4. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  5. Renal impairment (severely reduced kidney function)
  6. Blood glucose decreased
  7. Blood pressure decreased
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Death
  10. Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Restasis and Humulin N, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Blood glucose decreased
  5. Blood pressure decreased
  6. Cellulitis (infection under the skin)
  7. Cerebral atrophy (decrement in size of brain)
  8. Cerebral venous thrombosis (clot in brains venous blood system)
  9. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  10. Chronic kidney disease

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 53.33%
  2. High Blood Pressure: 3 people, 20.00%
  3. Hypergammaglobulinaemia (elevated levels of gamma globulin): 2 people, 13.33%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 13.33%
  5. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 2 people, 13.33%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
  7. Hiv Infection: 2 people, 13.33%
  8. Amino Acid Metabolism Disorder: 2 people, 13.33%
  9. Itching: 1 person, 6.67%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and Humulin n?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Restasis and Humulin n:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Humulin n:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Restasis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Humulin n and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and insulin susp isophane recombinant human (the active ingredients of Restasis and Humulin n, respectively), and Restasis and Humulin n (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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