Restasis and Lantus solostar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Lantus solostar (insulin glargine recombinant). Common drug interactions include joint dislocation among females and rash maculo-papular among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Lantus solostar. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Lantus solostar?

Lantus solostar has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 41,639 Lantus solostar users. Check the latest studies of Lantus solostar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

44 people who take Restasis and Lantus solostar together, and have interactions are studied.

Restasis and Lantus solostar drug interactions.

What are the common drug interactions of Restasis and Lantus Solostar, by gender? *:

female:

Joint dislocation (a joint position is changed from normal position)
Limb discomfort (discomfort in leg)
Liver disorder (liver diseases)
Lung infection
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Malaise (a feeling of general discomfort or uneasiness)
Migraine (headache)
Motion sickness (travel sickness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

male:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cataract (clouding of the lens inside the eye)
Death
Depression
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dyspepsia (indigestion)
Eye infection

What are the common drug interactions of Restasis and Lantus Solostar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Arthralgia (joint pain)
Blood pressure increased
Dyspnoea (difficult or laboured respiration)
Feeling hot
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Heart rate increased

50-59:

Rhinalgia (pain in the nose)
Social phobia (fear to go in social)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Urinary retention (the inability to completely or partially empty the bladder)
Urinary tract infection
Vomiting
Weight increased
Eye pain
Asthma

60+:

Dizziness
Epistaxis (bleed from the nose)
Blood glucose increased
Bone disorder
Chronic kidney disease
Cough
Death
Diarrhoea
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 7 people, 15.91%
Constipation: 6 people, 13.64%
Nausea (feeling of having an urge to vomit): 6 people, 13.64%
Cough: 6 people, 13.64%
Gout (uric acid crystals building up in the body): 5 people, 11.36%
Erythema Multiforme (a type of hypersensitivity reaction): 5 people, 11.36%
Back Pain: 5 people, 11.36%
Coughing Up Blood: 5 people, 11.36%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 5 people, 11.36%
Abdominal Pain Upper: 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

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