Restasis and Lucentis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Lucentis (ranibizumab). Common drug interactions include myalgia among females and vitreous floaters among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Lucentis. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Lucentis?

Lucentis has active ingredients of ranibizumab. It is often used in macular degeneration. eHealthMe is studying from 25,647 Lucentis users. Check the latest studies of Lucentis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

36 people who take Restasis and Lucentis together, and have interactions are studied.

Restasis and Lucentis drug interactions.

What are the common drug interactions of Restasis and Lucentis, by gender? *:

female:

Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Oral mucosal blistering (mouth ulcer)
Oral mucosal exfoliation (removal of mucous membrane of mouth)
Pruritus (severe itching of the skin)
Rash
Sensation of foreign body
Skin exfoliation (removal of the oldest dead skin cells)

male:

Vitreous floaters (spots before the eyes)
Pain
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Hemiparesis (weakness on one side of the body)
Keratopathy (noninflammatory disease of the cornea)
Stress
Vitreous detachment (a condition of the eye in which the vitreous humour separates from the retina)
Diarrhoea
Age-related macular degeneration
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)

What are the common drug interactions of Restasis and Lucentis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood urine present
Diarrhoea
Eye inflammation
Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
Platelet count decreased
Weight decreased
White blood cell count decreased

40-49:

n/a

50-59:

Discomfort
Eye pain
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Punctate keratitis (inflammation of the cornea with tiny spots)
Vision blurred
Visual impairment
Arthralgia (joint pain)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

60+:

Vision blurred
Blood glucose increased
Cystoid macular oedema (fluid accumulation after cataract surgery)
Hemiparesis (weakness on one side of the body)
Keratopathy (noninflammatory disease of the cornea)
Pain
Stress
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Drug hypersensitivity

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 16.67%
High Blood Cholesterol: 6 people, 16.67%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 6 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 13.89%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 5 people, 13.89%
Stress And Anxiety: 4 people, 11.11%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 3 people, 8.33%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 3 people, 8.33%
Vitreous Degeneration (serious vision problems in humans): 2 people, 5.56%
Urination - Excessive Volume: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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