Restasis and Multaq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Multaq (dronedarone hydrochloride). Common drug interactions include pruritus among females and eye irritation among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Multaq. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

On Aug, 02, 2026

37 people who take Restasis and Multaq together, and have interactions are studied.

What are the common drug interactions of Restasis and Multaq, by gender? *:

female:

Pruritus (severe itching of the skin)
Rash
Erythema (redness of the skin)
Glaucoma (increased fluid pressure in the eye with vision loss)
Urine calcium increased
Skin burning sensation
Anxiety
Dyspnoea (difficult or laboured respiration)
Feeling hot
Blood pressure increased

male:

Eye irritation
Dysphagia (a condition in which swallowing is difficult or painful)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Tinnitus (a ringing in the ears)
Tooth disorder (tooth disease)
Vitamin d decreased
Vitreous floaters (spots before the eyes)
Blood sodium decreased
Constipation
Cystitis (inflammation of the wall of the bladder)

What are the common drug interactions of Restasis and Multaq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Pneumonia

60+:

Anxiety
Dysphagia (a condition in which swallowing is difficult or painful)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hallucination (an experience involving the perception of something not present)
Heart rate increased
Muscular weakness (muscle weakness)
Weight decreased
Abdominal discomfort
Alanine aminotransferase increased
Anaemia (lack of blood)

What are the existing conditions these people have? *

Pain: 5 people, 13.51%
High Blood Cholesterol: 4 people, 10.81%
Headache (pain in head): 4 people, 10.81%
Cardiac Disorder: 4 people, 10.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 8.11%
Menopause (end of monthly cycles in women): 3 people, 8.11%
High Blood Pressure: 3 people, 8.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.11%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.41%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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