Restasis and Tagamet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Tagamet (cimetidine). Common drug interactions include cellulitis among females and feeling hot among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Tagamet. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

On Aug, 05, 2026

32 people who take Restasis and Tagamet together, and have interactions are studied.

What are the common drug interactions of Restasis and Tagamet, by gender? *:

female:

Cellulitis (infection under the skin)
Confusional state
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Osteomyelitis (infection of bone)
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Urinary tract infection
Visual acuity reduced (reduced clearness of vision)

male:

Feeling hot
Cardiac procedure complication
Eye pain
Hepatomegaly (abnormal enlargement of the liver)

What are the common drug interactions of Restasis and Tagamet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess (pus)
Anaemia of chronic disease
Anxiety
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood glucose increased
Blood pressure fluctuation

20-29:

Asthenia (weakness)
Back pain
Blood creatinine increased
Blood urea increased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)

30-39:

n/a

40-49:

Blood pressure increased
Cardiac flutter (abnormal heart rhythm)
Chest pain
Chronic kidney disease
Heart rate increased
Renal failure (kidney dysfunction)

50-59:

n/a

60+:

Pain
Anxiety
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Urinary tract infection
Visual acuity reduced (reduced clearness of vision)
Vomiting
Abscess (pus)
Anaemia of chronic disease

What are the existing conditions these people have? *

Multiple Allergies (allergy to multiple agents): 4 people, 12.50%
Pain: 3 people, 9.38%
Osteoporosis (bones weak and more likely to break): 3 people, 9.38%
High Blood Pressure: 3 people, 9.38%
Sinusitis (inflammation of sinus): 2 people, 6.25%
Parkinson's Disease: 2 people, 6.25%
Neuralgia (pain in one or more nerves): 2 people, 6.25%
Inflammation: 2 people, 6.25%
Infection: 2 people, 6.25%
Hypokalemia (low potassium): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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