Restoril and Cleocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restoril (temazepam) and Cleocin (clindamycin phosphate). Common drug interactions include asthenia among females and general physical health deterioration among males.

The phase IV clinical study analyzes what interactions people have when they take Restoril and Cleocin. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

What is Cleocin?

Cleocin has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 3,940 Cleocin users. Check the latest studies of Cleocin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

38 people who take Restoril and Cleocin together, and have interactions are studied.

What are the common drug interactions of Restoril and Cleocin, by gender? *:

female:

Asthenia (weakness)
Cataract (clouding of the lens inside the eye)
Deformity (disfigurement)
Emotional distress
Fall
Gingival bleeding (bleeding gums)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypophagia (reduced food intake)
Impaired healing
Onychomycosis (fungal infection of the nail)

male:

General physical health deterioration (weak health status)
Pain
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac valve abscess (pus containing infection of heart valve)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Constipation
Decreased interest
Deformity (disfigurement)
Diarrhoea

What are the common drug interactions of Restoril and Cleocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypertension (high blood pressure)
Blood glucose increased
Depression
Haematocrit decreased
Haemoglobin decreased
Hyperlipidaemia (presence of excess lipids in the blood)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Pitting oedema (skin discoloration)

40-49:

Abdominal pain
Abscess jaw (tooth abscess or root abscess)
Actinic keratosis (skin disease due to sun exposure)
Aggression
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)

50-59:

Weight decreased
Abdominal pain upper
Anaemia (lack of blood)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood cholesterol increased
Bone disorder

60+:

Dizziness
Fatigue (feeling of tiredness)
Osteomyelitis (infection of bone)
Osteonecrosis of jaw (death of bone of jaw)
Anaemia (lack of blood)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Abscess jaw (tooth abscess or root abscess)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Angina pectoris (chest pain due to ischemia of the heart muscle)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 19 people, 50.00%
High Blood Pressure: 4 people, 10.53%
Depression: 4 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.89%
Nausea (feeling of having an urge to vomit): 3 people, 7.89%
Constipation: 3 people, 7.89%
Stress And Anxiety: 2 people, 5.26%
Sleep Disorder: 2 people, 5.26%
Pain: 2 people, 5.26%
Muscle Spasms (muscle contraction): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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