Retin-a and Folvite drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Retin-a (tretinoin) and Folvite (folic acid). Common drug interactions include constipation among females and activated partial thromboplastin time shortened among males.

The phase IV clinical study analyzes what interactions people have when they take Retin-a and Folvite. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Retin-a?

Retin-a has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 2,475 Retin-a users. Check the latest studies of Retin-a.

What is Folvite?

Folvite has active ingredients of folic acid. eHealthMe is studying from 2,529 Folvite users. Check the latest studies of Folvite.

On Jul, 25, 2026

11 people who take Retin-a and Folvite together, and have interactions are studied.

What are the common drug interactions of Retin-A and Folvite, by gender? *:

female:

Constipation
Eating disorder
Faeces discoloured
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Nausea (feeling of having an urge to vomit)
Suicidal ideation
Coeliac artery stenosis (abnormal narrowing of coeliac artery)
Gastric ulcer (stomach ulcer)
Helicobacter test positive
Urinary tract infection

male:

Activated partial thromboplastin time shortened
Anaemia (lack of blood)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Transaminases increased
Urinary tract infection
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the common drug interactions of Retin-A and Folvite, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Suicidal ideation

40-49:

n/a

50-59:

n/a

60+:

Activated partial thromboplastin time shortened
Anaemia (lack of blood)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Transaminases increased
Urinary tract infection
Aspartate aminotransferase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the existing conditions these people have? *

Depression: 4 people, 36.36%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 27.27%
Hypovolaemia (a decreased volume of circulating blood in the body): 3 people, 27.27%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 27.27%
Diarrhea: 3 people, 27.27%
Electrolyte Imbalance: 3 people, 27.27%
Endophthalmitis (inflammation of the internal coats of the eye): 3 people, 27.27%
Hypotension (abnormally low blood pressure): 3 people, 27.27%
Skin Papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections): 3 people, 27.27%
Actinic Keratosis (skin disease due to sun exposure): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

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