Retin-a and Multivitamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Retin-a (tretinoin) and Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include application site erythema among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Retin-a and Multivitamin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Retin-a?

Retin-a has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 2,475 Retin-a users. Check the latest studies of Retin-a.

What is Multivitamin?

Multivitamin has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 83,597 Multivitamin users. Check the latest studies of Multivitamin.

On Jul, 27, 2026

41 people who take Retin-a and Multivitamin together, and have interactions are studied.

Retin-a and Multivitamin drug interactions.

What are the common drug interactions of Retin-A and Multivitamin, by gender? *:

female:

Application site erythema (redness of the skin at application site)
Application site irritation
Application site pruritus (application site severe itching of the skin)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back injury
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Fatigue (feeling of tiredness)
Diarrhoea

male:

Anxiety
Decreased appetite
Rash
Sinusitis (inflammation of sinus)
Thirst
Drug hypersensitivity
Dry mouth
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Face oedema (swelling of face)

What are the common drug interactions of Retin-A and Multivitamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Decreased appetite
Drug hypersensitivity
Dry mouth
Dyspepsia (indigestion)
Face oedema (swelling of face)
Hyperventilation
Muscle spasms (muscle contraction)
Nasopharyngitis (inflammation of the nasopharynx)
Rash

20-29:

Feeling hot
Injection site bruising
Injection site pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Photosensitivity reaction
Rash
Sinusitis (inflammation of sinus)

30-39:

Abnormal sensation in eye
Abortion induced (medically referred abortion)
Blood potassium decreased
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Eye disorder
Hemiparesis (weakness on one side of the body)
Hypersensitivity
Neuropathy peripheral (surface nerve damage)
Skin burning sensation
Skin injury

40-49:

Back injury
Chills (felling of cold)
Malaise (a feeling of general discomfort or uneasiness)
Neuropathy peripheral (surface nerve damage)
Night sweats (sweating in night)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)

50-59:

Osteonecrosis of jaw (death of bone of jaw)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteosclerosis (an elevation in bone density)
Pancreatitis acute (sudden inflammation of pancreas)
Pleural effusion (water on the lungs)
Proteinuria (presence of protein in the urine)
Pruritus (severe itching of the skin)
Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
Rash
Renal failure (kidney dysfunction)

60+:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chest pain
Chills (felling of cold)
Constipation

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 17.07%
Migraine (headache): 4 people, 9.76%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 9.76%
Skin Wrinkling (wrinkle on skin): 3 people, 7.32%
Osteoporosis (bones weak and more likely to break): 3 people, 7.32%
Multiple Myeloma (cancer of the plasma cells): 3 people, 7.32%
Bone Density Decreased: 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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