Revatio and Macitentan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Revatio (sildenafil citrate) and Macitentan (macitentan). Common drug interactions include fluid retention among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Revatio and Macitentan. It is created by eHealthMe based on reports of 560 people who take the same drugs from the FDA, and is updated regularly.
What is Revatio?
Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.
What is Macitentan?
Macitentan has active ingredients of macitentan. eHealthMe is studying from 7,371 Macitentan users. Check the latest studies of Macitentan.
560 people who take Revatio and Macitentan together, and have interactions are studied.

What are the common drug interactions of Revatio and Macitentan, by gender? *
What are the common drug interactions of Revatio and Macitentan, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Revatio and Macitentan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Revatio (44,849 reports)
- Macitentan (7,371 reports)
Browse all drug interactions of Revatio and Macitentan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Macitentan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revatio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Macitentan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on sildenafil citrate and macitentan (the active ingredients of Revatio and Macitentan, respectively), and Revatio and Macitentan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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