Revatio and Sulfamethoxazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Revatio (sildenafil citrate) and Sulfamethoxazole (sulfamethoxazole). Common drug interactions include back pain among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Revatio and Sulfamethoxazole. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

On Jul, 09, 2026

11 people who take Revatio and Sulfamethoxazole together, and have interactions are studied.

Revatio and Sulfamethoxazole drug interactions.

What are the common drug interactions of Revatio and Sulfamethoxazole, by gender? *:

female:

Back pain
Cold sweat
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Septic shock (shock due to blood infection)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Swelling face
Local swelling (swelling at the site of some application of substance or injury)
Peripheral swelling

male:

Death
Diarrhoea
Abdominal distension
Adrenal disorder
Palpitations (feelings or sensations that your heart is pounding or racing)
Disturbance in attention
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oedema (fluid collection in tissue)

What are the common drug interactions of Revatio and Sulfamethoxazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Disturbance in attention
Fatigue (feeling of tiredness)
Flatulence (flatus expelled through the anus)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Somnambulism (sleep walking)
Swelling face
Thirst

50-59:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Septic shock (shock due to blood infection)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Abdominal distension
Adrenal disorder
Palpitations (feelings or sensations that your heart is pounding or racing)

60+:

Back pain
Cold sweat

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 63.64%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 18.18%
Embolism Venous (embolus may pass into the arterial system): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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