Revatio and Tiotropium bromide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Revatio (sildenafil citrate) and Tiotropium bromide (tiotropium bromide). Common drug interactions include menopause among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Revatio and Tiotropium bromide. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

What is Tiotropium bromide?

Tiotropium bromide has active ingredients of tiotropium bromide. eHealthMe is studying from 7,688 Tiotropium bromide users. Check the latest studies of Tiotropium bromide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

14 people who take Revatio and Tiotropium bromide together, and have interactions are studied.

Revatio and Tiotropium bromide drug interactions.

What are the common drug interactions of Revatio and Tiotropium Bromide, by gender? *:

female:

Menopause (end of monthly cycles in women)
Migraine (headache)
Mobility decreased (ability to move is reduced)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Overweight
Pain
Palmar erythema (reddening of the palms at the thenar and hypothenar eminences)

male:

Dyspnoea (difficult or laboured respiration)
Deafness bilateral
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Asthma
Cellulitis (infection under the skin)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypoxia (low oxygen in tissues)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Pulmonary arterial wedge pressure increased

What are the common drug interactions of Revatio and Tiotropium Bromide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Staphylococcal infection (an infection with staphylococcus bacteria)
Upper respiratory tract infection
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Back pain
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Fatigue (feeling of tiredness)

60+:

Dyspnoea (difficult or laboured respiration)
Deafness bilateral
Headache (pain in head)
Influenza like illness
Neuralgia (pain in one or more nerves)
Oedema (fluid collection in tissue)
Peripheral swelling
Pyrexia (fever)
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
Weight decreased

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 42.86%
Right Ventricular Failure (right half of the heart fails to work): 3 people, 21.43%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 14.29%
Primary Myelofibrosis (primary disorder of the bone marrow): 1 person, 7.14%
Infection: 1 person, 7.14%
Cardiac Failure Congestive: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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