Revlimid and Actemra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Revlimid (lenalidomide) and Actemra (tocilizumab). Common drug interactions include infusion related reaction among females and disease progression among males.
The phase IV clinical study analyzes what interactions people have when they take Revlimid and Actemra. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Revlimid?
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.
What is Actemra?
Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.
26 people who take Revlimid and Actemra together, and have interactions are studied.

What are the common drug interactions of Revlimid and Actemra, by gender? *:
female:
- Infusion related reaction
- Abdominal distension
- Allergic respiratory symptom
- Contusion (a type of hematoma of tissue in which capillaries)
- Dyspnoea (difficult or laboured respiration)
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
- Hypersensitivity
- Hypertension (high blood pressure)
- Ill-defined disorder
- Inflammation
male:
- Disease progression
- Jc virus infection
- Fatigue (feeling of tiredness)
- Cardiac failure congestive
- Death
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
- Hypotonia (low muscle tone)
- Oropharyngeal pain
- Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
- Sepsis (a severe blood infection that can lead to organ failure and death)
What are the common drug interactions of Revlimid and Actemra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Disease progression
- Jc virus infection
- Mantle cell lymphoma recurrent (cancer of lymphocytes, a type of white blood cell- recurrent)
- Abdominal distension
- Allergic respiratory symptom
- Contusion (a type of hematoma of tissue in which capillaries)
- Dyspnoea (difficult or laboured respiration)
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
- Hypersensitivity
- Hypertension (high blood pressure)
60+:
- Arthralgia (joint pain)
- Cough
- Gout (uric acid crystals building up in the body)
- Hypoaesthesia (reduced sense of touch or sensation)
- Infusion related reaction
- Nausea (feeling of having an urge to vomit)
- Weight decreased
- Cardiac failure congestive
- Swelling
- Neuropathy peripheral (surface nerve damage)
What are the existing conditions these people have? *
- Mantle Cell Lymphoma Refractory (relapsed cancer of lymphocytes, a type of white blood cell): 6 people, 23.08%
- High Blood Pressure: 6 people, 23.08%
- Fever: 6 people, 23.08%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 5 people, 19.23%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 3 people, 11.54%
- Pain: 2 people, 7.69%
- Nausea (feeling of having an urge to vomit): 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Revlimid and Actemra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Revlimid and Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revlimid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actemra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lenalidomide and tocilizumab (the active ingredients of Revlimid and Actemra, respectively), and Revlimid and Actemra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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