Revlimid and Nplate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Revlimid (lenalidomide) and Nplate (romiplostim). Common drug interactions include hypogammaglobulinaemia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Revlimid and Nplate. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Revlimid?

Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.



On Jul, 21, 2026

52 people who take Revlimid and Nplate together, and have interactions are studied.

Revlimid and Nplate drug interactions.

What are the common drug interactions of Revlimid and Nplate, by gender? *:

female:

  1. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
  2. Interstitial lung disease
  3. Joint dislocation (a joint position is changed from normal position)
  4. Myelodysplastic syndrome transformation (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged and gets changed into rapid progressing cancer)
  5. Myeloproliferative disorder (a group of diseases in which the bone marrow makes too many red blood cells, white blood cells, or platelets)
  6. Neuropathy peripheral (surface nerve damage)
  7. Neutropenia (an abnormally low number of neutrophils)
  8. Oedema peripheral (superficial swelling)
  9. Oropharyngeal candidiasis (fungal infection of oropharynx)
  10. Osteoporosis (bones weak and more likely to break)

male:

  1. Diarrhoea
  2. Rash
  3. Drug intolerance (drug sensitivity)
  4. Glaucoma (increased fluid pressure in the eye with vision loss)
  5. Infection
  6. Sudden death
  7. Pneumonia
  8. Respiratory tract infection
  9. Cardiogenic shock (inadequate circulation of blood)
  10. Surgery

What are the common drug interactions of Revlimid and Nplate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain in extremity
  2. Vomiting
  3. Human chorionic gonadotropin increased
  4. Rash pruritic (redness with itching)
  5. Abdominal discomfort
  6. Chills (felling of cold)
  7. Fatigue (feeling of tiredness)

50-59:

  1. Chills (felling of cold)
  2. Death
  3. Hypoaesthesia (reduced sense of touch or sensation)

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Anaemia (lack of blood)
  3. Glaucoma (increased fluid pressure in the eye with vision loss)
  4. Infection
  5. Rash
  6. Sudden death
  7. Pneumonia
  8. Cardiogenic shock (inadequate circulation of blood)
  9. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  10. Respiratory tract infection

What are the existing conditions these people have? *

  1. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 16 people, 30.77%
  2. Thrombocytopenia (decrease of platelets in blood): 4 people, 7.69%
  3. Cytomegalovirus Infection: 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

Do you take Revlimid and Nplate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Revlimid and Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Revlimid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nplate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Revlimid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nplate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lenalidomide and romiplostim (the active ingredients of Revlimid and Nplate, respectively), and Revlimid and Nplate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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