Revlimid and Trileptal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Revlimid (lenalidomide) and Trileptal (oxcarbazepine). Common drug interactions include incontinence among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Revlimid and Trileptal. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.
What is Revlimid?
Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.
60 people who take Revlimid and Trileptal together, and have interactions are studied.

What are the common drug interactions of Revlimid and Trileptal, by gender? *:
female:
- Incontinence (lack of moderation or self-control)
- Motion sickness (travel sickness)
- Red blood cell count decreased
- Vomiting
- White blood cell count decreased
- Abscess jaw (tooth abscess or root abscess)
- Accident at home
- Acute myocardial infarction (acute heart attack)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthralgia (joint pain)
male:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Asthma
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Fall
- Gout (uric acid crystals building up in the body)
- Haematuria (presence of blood in urine)
- Heat stroke
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
What are the common drug interactions of Revlimid and Trileptal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hepatic failure (liver failure)
- Leukopenia (less number of white blood cells in blood)
- Neoplasm progression (growth of tumour)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
20-29:
n/a
30-39:
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
40-49:
- Anaemia (lack of blood)
- Asthenia (weakness)
- Constipation
- Cough
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Haematocrit decreased
- Haemoglobin decreased
- Lethargy (tiredness)
50-59:
n/a
60+:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dehydration (dryness resulting from the removal of water)
- Gout (uric acid crystals building up in the body)
- Haematuria (presence of blood in urine)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypokalaemia (low potassium)
What are the existing conditions these people have? *
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 5 people, 8.33%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 6.67%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 5.00%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Revlimid and Trileptal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Revlimid and Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Revlimid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revlimid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trileptal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lenalidomide and oxcarbazepine (the active ingredients of Revlimid and Trileptal, respectively), and Revlimid and Trileptal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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