Rexulti and Dyazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rexulti (brexpiprazole) and Dyazide (hydrochlorothiazide; triamterene). Common drug interactions include asthma among females.

The phase IV clinical study analyzes what interactions people have when they take Rexulti and Dyazide. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Rexulti?

Rexulti has active ingredients of brexpiprazole. It is often used in major depression. eHealthMe is studying from 13,394 Rexulti users. Check the latest studies of Rexulti.

What is Dyazide?

Dyazide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 11,506 Dyazide users. Check the latest studies of Dyazide.

On Jul, 09, 2026

19 people who take Rexulti and Dyazide together, and have interactions are studied.

What are the common drug interactions of Rexulti and Dyazide, by gender? *:

female:

Asthma
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hospitalisation
Memory impairment
Nephrolithiasis (calculi in the kidneys)
Ocular myasthenia (a disease of the neuromuscular junction resulting in hallmark variability in muscle weakness and fatigability)
Restless legs syndrome (a powerful urge to move your legs)
Retinal vascular disorder (a range of eye diseases that affect the blood vessels in the eye)
Vitamin d deficiency

male:

n/a

What are the common drug interactions of Rexulti and Dyazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cystitis (inflammation of the wall of the bladder)
Hospitalisation
Memory impairment
Spinal fusion surgery
Asthma
Diplopia (double vision)
Hysterectomy
Pain
Poor quality sleep
Retinal vascular disorder (a range of eye diseases that affect the blood vessels in the eye)

50-59:

Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Dental care
Vitamin d deficiency
Peripheral swelling
Rash
Thrombocytosis
Tinnitus (a ringing in the ears)
Asthma
Chronic kidney disease
Epicondylitis (tennis elbow)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 100.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 68.42%
Drowsiness: 2 people, 10.53%
Rosacea (a skin condition that causes facial redness): 1 person, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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