Rezulin and Motrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rezulin (troglitazone) and Motrin (ibuprofen). Common drug interactions include atrial fibrillation among females and blood urea increased among males.

The phase IV clinical study analyzes what interactions people have when they take Rezulin and Motrin. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Rezulin?

Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

On Jul, 09, 2026

76 people who take Rezulin and Motrin together, and have interactions are studied.

What are the common drug interactions of Rezulin and Motrin, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Confusional state
Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Red blood cell count decreased
Anaemia (lack of blood)
Chest pain
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus inadequate control

male:

Blood urea increased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Agitation (state of anxiety or nervous excitement)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arthralgia (joint pain)
Cardiomegaly (increased size of heart than normal)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Erythema (redness of the skin)

What are the common drug interactions of Rezulin and Motrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Atelectasis (partial or complete collapse of the lung)
Chest pain
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Gastritis (inflammation of stomach)
Road traffic accident
Vomiting
Abdominal pain
Abdominal pain lower

40-49:

Diarrhoea
Hepatocellular damage (liver damage)
Abdominal discomfort
Abdominal distension
Acute respiratory distress syndrome
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Anasarca (general swelling, or massive oedema)
Anxiety
Arrhythmia (irregular heartbeat)

50-59:

Fatigue (feeling of tiredness)
International normalised ratio increased
Pneumonia
Anxiety
Arthralgia (joint pain)
Dehydration (dryness resulting from the removal of water)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Impaired healing
Inflammation
Neck pain

60+:

Blood urea increased
Haemoglobin decreased
Confusion
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Urinary tract infection
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 7 people, 9.21%
Breast Cancer: 7 people, 9.21%

* Approximation only. Some reports may have incomplete information.

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